Journal of Isfahan Medical School

Journal of Isfahan Medical School

Microbial resistance pattern and antibiogram results in children with urinary tract infections in Shahrekord 2025; a cross-sectional descriptive-analytical study

Document Type : Original Article (s)

Authors
Elham Emami 1
Atrin Oroojeni 2
Panteha Oroojeni 3
1 Assistant Professor, Department of Paediatrics, Faculty of Medicine, Shahrekord University of Medical Sciences, Shahrekord, Iran
2 Faculty of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
3 Department of Nursing and Midwifery, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
10.48305/jims.v44.i850.0100
Abstract
Background: The increasing antimicrobial resistance in pediatric urinary tract infections (UTIs) has complicated empirical treatment of these infections. This study aimed to determine the antibiotic resistance pattern and to evaluate antibiogram results in children with UTIs presenting to Hajar Hospital (Shahrekord) and Imam Ali Clinic during 2024–2025.
Methods : In this cross-sectional (descriptive-analytical) study, children under 15 years of age with positive urine cultures who presented to the above centers were enrolled by census. Demographic data and antibiogram results were collected and analyzed using SPSS version 21. Chi-square and independent t-tests were used to examine associations between variables, and a p-value < 0.05 was considered statistically significant.
Findings: The results showed that the prevalence of UTIs was significantly higher in females than in males. Escherichia coli was identified as the most frequent microbial agent, followed by Klebsiella species and other pathogens. The antibiotic resistance profile indicated high resistance of the pathogens to cotrimoxazole (63.3%) and ciprofloxacin (39%). Relatively high resistance was also observed to cefotaxime (64%) and ceftriaxone (36.8%). In contrast, the highest antibiotic susceptibilities were seen for imipenem (3.6% resistance), nitrofurantoin (1.9% resistance), and amikacin (0% resistance). A statistically significant association was also found between constipation and the occurrence of UTIs.
Conclusion : The findings underscore the need to revise empirical treatment protocols for pediatric UTIs, to continuously monitor microbial resistance, and to consider clinical risk factors such as sex and constipation.

Highlights

Elham Emami :Google Scholar

Atrin Oroojeni : Google Scholar , PubMed

Keywords
Urinary Tract Infection
Drug Resistance
Child

Subjects

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Journal of Isfahan Medical School
Volume 44, Issue 850
2nd Week, April
March and April 2026
Pages 100-107

  • Receive Date 28 January 2026
  • Accept Date 09 February 2026