Journal of Isfahan Medical School

Journal of Isfahan Medical School

The relationship between exposure to a number of allergens and pathogens during pregnancy with anthropometric indicators of infants in Yazd

Document Type : Original Article(s)

Authors
1 PhD in Reproductive Health, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran
2 Fellowship in Perinatology, Department of Obstetrics and Gynecology, Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
3 PhD in Reproductive Health Research Center for Nursing and Midwifery Care, Comprehensive Research Institute for Maternal and Child Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
4 Assistant Professor, Department of Genetics, Research Center for Genetics and Environmental Hazards, School of Paramedical Sciences, Abarkuh, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
5 Assistant Professor, Department of Social Medicine, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
10.48305/jims.v44.i850.0075
Abstract
Backgroud :Pregnant women are exposed daily to various allergens and pathogens that may influence infant growth indices. This study aimed to investigate the association between exposure to selected allergens and pathogens during pregnancy and anthropometric indices at birth.

Methods: This prospective cohort study was conducted in four referral obstetrics and gynecology hospitals in Yazd, Iran. The study population included all eligible pregnant women (n=1,623) who visited these referral centers from 2014 to 2019, selected through a census method. Data collection tools included a demographic characteristics form, infant anthropometric indices, and maternal exposure history to allergens and pathogens during pregnancy. Data were analyzed using SPSS version 22.

Findings: A significant association was found between exposure to mobile phone towers and high-voltage power lines and infant height (p≤0.05). Increased exposure to mobile phone towers was associated with decreased infant height, while exposure to high-voltage power lines was linked to increased infant height. No significant associations were observed between exposure to other allergens or pathogens and anthropometric indices (p>0.05).

Conclusion: The findings indicate a significant relationship between electromagnetic wave exposure and infant height. However, factors such as the intensity, duration, and distance of exposure to electromagnetic waves warrant further investigation.

Highlights

Zahra Mohebbi Dehnavi: PubMed , Google Scholar

 Razieh Sadat Tabatabaei: Google Scholar

 Leila Asadi: PubMed , Google Scholar

 Ali Dadbinpour: Google Scholar

Mahmoud Vakili Ghasemabad: Google Scholar

Keywords

Subjects


1.     Souza JP, Day LT, Rezende-Gomes AC, Zhang J, Mori R, Baguiya A, et al. A global analysis of the determinants of maternal health and transitions in maternal mortality. Lancet Glob Health 2024; 12(2): e306-e316.
2.     Ahmadi Taheri S RAA, Barikani A. Comparison of dietary patterns during pregnancy in mothers with low birth weight and normal birth weight children [in Persian]. Iranian Journal of Obstetrics, Gynecology and Infertility 2018; 21(1): 80-9.
3.     Arnold L, Hoy W, Wang Z. Low birthweight increases risk for cardiovascular disease hospitalisations in a remote Indigenous Australian community–a prospective cohort study. Aust N Z J Public Health 2016; 40(S1): S102-S6.
4.     Stamnes Koepp UM, Frost Andersen L, Dahl‐Joergensen K, Stigum H, Nass O, Nystad W. Maternal pre‐pregnant body mass index, maternal weight change and offspring birthweight. Acta Obstet Gynecol Scand 2012; 91(2): 243-9.
5.     Alam MJ, Islam MM, Maniruzzaman M, Ahmed NF, Tawabunnahar M, Rahman MJ, et al. Socioeconomic inequality in the prevalence of low birth weight and its associated determinants in Bangladesh. PLoS One 2022; 17(10): e0276718.
6.     Tang Z, Long X, Wang K, Berger K, Zhang Y, Mayvaneh F. Risk and burden of low birthweight related to maternal PM2. 5 exposure in Iran: A national causal inference study. Ecotoxicol Environ Saf 2024; 288: 117414.
7.     Luo S, Wang Y, Mayvaneh F, Relvas H, Baaghideh M, Wang K, et al. Surrounding greenness is associated with lower risk and burden of low birth weight in Iran. Nat Commun 2023; 14(1): 7595.
8.     Moghtaderi M, Teshnizi SH, Farjadian S. Sensitization to common allergens among patients with allergies in major Iranian cities: a systematic review and meta-analysis. Epidemiol Health 2017; 39: e2017007.
9.     Razavimoghadam M, Sefidkar R, Ehrampoush MH, Teimouri F, Hassanabadi MHZ, Nokhostin F. The association of widely used electromagnetic waves exposure and pregnancy and birth outcomes in Yazd women: a cohort study. BMC Pregnancy and Childbirth 2025; 25(1): 427.
10.  Adanikin A, Lawlor DA, Pell JP, Nelson SM, Smith GC, Iliodromiti S. Association of birthweight centiles and early childhood development of singleton infants born from 37 weeks of gestation in Scotland: A population-based cohort study. PLoS Med 2022; 19(10): e1004108.
11.  Aoyama T, Li D, Bay JL. Weight gain and nutrition during pregnancy: an analysis of clinical practice guidelines in the Asia-Pacific region. Nutrients 2022; 14(6): 1288.
12.  Ren Y, Chen J, Miao M, Li D-K, Liang H, Wang Z, et al. Prenatal exposure to extremely low frequency magnetic field and its impact on fetal growth. Environ Health 2019; 18: 6.
13.  Migault L, Piel C, Carles C, Delva F, Lacourt A, Cardis E, et al. Maternal cumulative exposure to extremely low frequency electromagnetic fields and pregnancy outcomes in the Elfe cohort. Environ Int 2018; 112: 165-73.
14.  Kashani ZA, Pakzad R, Fakari FR, Haghparast MS, Abdi F, Kiani Z, et al. Electromagnetic fields exposure on fetal and childhood abnormalities: Systematic review and meta-analysis. Open Med (Wars) 2023; 18(1): 20230697.
15.  Patterson WB, Glasson J, Naik N, Jones RB, Berger PK, Plows JF, et al. Prenatal exposure to ambient air pollutants and early infant growth and adiposity in the Southern California Mother’s Milk Study. Environ Health 2021; 20(1): 67.
16.  Kalloo G, Wellenius GA, McCandless L, Calafat AM, Sjodin A, Romano ME, et al. Exposures to chemical mixtures during pregnancy and neonatal outcomes: the HOME study. Environ Int 2020; 134: 105219.
17.  Eick SM, Tan Y, Taibl KR, Barry Ryan P, Barr DB, Hüls A, et al. Prenatal exposure to persistent and non-persistent chemical mixtures and associations with adverse birth outcomes in the Atlanta African American Maternal-Child Cohort. J Expo Sci Environ Epidemiol 2024; 34(4):5 70-80.
18.  Fadaei S, Pourzamani H, Ebrahimpour K, Feizi A, Daniali SS, Kelishadi R. Association of maternal urinary concentration of parabens and neonatal anthropometric indices. J Environ Health Sci Eng 2020; 18(2): 617-28.
19.  Bräuner EV, Uldbjerg CS, Beck AL, Lim Y-H, Boye H, Frederiksen H, et al. Prenatal paraben exposures and birth size: Sex-specific associations in a healthy population-A study from the Odense Child Cohort. Sci Total Environ 2023; 869: 161748.
20.  Jin S, Cui S, Xu J, Zhang X. Associations between prenatal exposure to phthalates and birth weight: a meta-analysis study. Ecotoxicol Environ Saf 2023; 262: 115207.
21.  Santos PC, Telmo PdL, Lehmann LM, Mattos GT, Klafke GB, Lorenzi C, et al. Risk and other factors associated with toxoplasmosis and toxocariasis in pregnant women from southern Brazil. J Helminthol 2017; 91(5): 534-8.
22.  Parvin I, Das SK, Ahmed S, Rahman A, Shahid ASMSB, Shahrin L, et al. Toxoplasma gondii Infection Is Associated with Low Birth Weight: Findings from an Observational Study among Rural Bangladeshi Women. Pathogens 2022; 11(3): 336.
23.  Liu W, Huang C, Cai J, Wang X, Zou Z, Sun C. Household environmental exposures during gestation and birth outcomes: A cross-sectional study in Shanghai, China. Science of The Total Environment 2018; 615: 1110-8.
24.  Lu C, Deng M, Norbäck D, Liu Z, Murithi RG, Deng Q. Effect of outdoor air pollution and indoor environmental factors on small for gestational age. Building and Environment 2021; 206: 108399.
Volume 44, Issue 850
2nd Week, April
March and April 2026
Pages 75-82

  • Receive Date 27 February 2025
  • Accept Date 04 January 2026