Journal of Isfahan Medical School

Journal of Isfahan Medical School

Comparing the Effectiveness of Cognitive-Behavioral Therapy and Exercise Therapy on the Tolerance of Ambiguity and Psychological Distress in Heart Failure Patients

Document Type : Original Article (s)

Authors
1 MSc in Medical-Surgical Nursing, Student Research Committee, Najafabad Branch, Islamic Azad University, Najafabad, Iran
2 MSc in Psychiatric Nursing, Community Health Research Center, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran
3 MSc in Medical-surgical Nursing, Research Center for Development of Nursing and Midwifery Sciences, Najafabad Branch, Islamic Azad University, Najafabad, Iran
4 Associate Professor, Department of Disasters and Emergencies, Community-Oriented Nursing Midwifery Research Center, Nursing and Midwifery School, Shahrekord University of Medical Sciences, Shahrekord, Iran
10.48305/jims.v44.i853.0269
Abstract
Introduction: Cardiovascular diseases are the most common cause of human mortality in the world. This study was conducted to compare the effectiveness of cognitive-behavioral therapy and exercise therapy on the tolerance of ambiguity and psychological distress in heart failure patients.
Methods: This study was applied in terms of purpose and quasi-experimental in terms of method with a pre-test-post-test design with a control group. The statistical population included all heart failure patients at Hajar Hospital, Shahrekord in 1404. Of these, 45 people were selected using convenience sampling and randomly assigned to three groups of 15 people (control, exercise therapy, cognitive-behavioral therapy).
Findings: The results obtained from multivariate analysis of covariance showed that there was a significant difference between the post-test scores of psychological distress and tolerance of ambiguity between the experimental and control groups (P < 0.05). The data were analyzed using multivariate analysis of covariance (MANCOVA) and independent t-test in SPSS-27 software. Findings: The results of multivariate analysis of covariance showed that both interventions resulted in a significant reduction in psychological distress and a significant increase in tolerance of ambiguity compared to the control group (P < 0.05).
Discussion and Conclusion: The findings support the effectiveness of both intervention approaches, but show a significant superiority of cognitive-behavioral therapy over exercise therapy in improving the psychological outcomes studied. It is suggested that this intervention be considered as a complementary component in comprehensive care programs for heart failure patients.

Highlights

 Alireza Seyfi Ardali: PubMed

Keywords
Subjects

1.     Shojaei F. Quality of Life in Patients with Heart Failure [in Persian]. Journal of Hayat 2008; 14(2): 5-13.
2.     Khorrami Estakhri R, Zakeri Moghaddam M. Effective factors on outcomes of heart failure disease: a review article [in Persian]. Cardiovascular Nursing Journal 2018; 7(3): 58-67.
3.     Khader M, Tan E, Toh B, Diong S-m, Chua S. Crisis Leadership: A Guide for Leaders. World Scientific; 2023.
4.     Dudley-Javoroski S, Cooper CS, Jackson JB, Zorn A, Carter KD, Shields RK. Tolerance for ambiguity: Correlations with medical and physical therapy student traits and experiences within the learning environment. Acad Med 2024; 99(6): 644-653..
5.     Furnham A, Marks J. Tolerance of ambiguity: A review of the recent literature. Psychol 2013; 4(9): 717-28.
6.     McEvoy PM, Mahoney AEJ. To be sure, to be sure: intolerance of uncertainty mediates symptoms of various anxiety disorders. J Anxiety Disord 2012; 26(3): 533–45.
7.     Celano CM, Villegas AC, Albanese AM, Gaggin HK, Huffman JC. Depression and anxiety in heart failure: A review. Harv Rev Psychiatry 2018; 26(4): 175–84.
8.     Fink G. Stress: Concepts, Cognition, Emotion, and Behavior: Handbook of Stress Series. 1st ed. London: Academic Press; 2016.
9.     Fallah Mh, Hossieni H, Fallahzadeh H, Mirzaei M. The relationship between depression, anxiety, stress, and physical activity with cardiovascular disease risk, using structural equation modeling in adults in Yazd City [in Persian]. Tolooebehdasht 2021; 20(3): 59-74.
10.  Zvolensky MJ, Vujanovic AA, Bernstein A, Leyro T. Distress tolerance: Theory, measurement, and relations to psychopathology. Curr Dir Psychol Sci 2010; 19(6): 406-10.
11.  Ebrahimzade S, SOHRABI F. Predicting addiction tendency based on the variables of psychological hardiness and intolerance of ambiguity in university students [in Persian]. Research on Addiction 2021; 15(61): 283-302.
12.  Taylor RS, Long L, Mordi IR, Tvilling Madsen M, Davies EJ, Dalal H, et al. Exercise-Based Rehabilitation for Heart Failure: Cochrane Systematic Review, Meta-Analysis, and Trial Sequential Analysis. JACC Heart Fail 2019; 7(8): 691-705.
13.  Tu RH, Zeng ZY, Zhong GQ, Wu WF, Lu YJ, Bo ZD, et al. Effects of exercise training on depression in patients with heart failure: a systematic review and meta-analysis of randomized controlled trials. Eur J Heart Fail 2014;16(7): 749-57
14.  Mohebbi B, Sabouri M, Tol A. Application of health education and promotion theory-based interventions on patients with cardiovascular disease: A systematic review. J Educ Health Promot 2021; 10: 236.
15.  Kitsiou S, Vatani H, Paré G, Gerber BS, Buchholz SW, Kansal MM, et al. Effectiveness of mobile health technology interventions for patients with heart failure: systematic review and meta-analysis. Can J Cardiol 2021; 37(8): 1248-59.
16.  Carleton RN. Fear of the unknown: One fear to rule them all? J Anxiety Disord. 2016; 41: 5-21.
17.  Bandura A. Self-efficacy: Toward a unifying theory of behavioral change. Psychol Rev 1977; 84(2): 191–215.
18.  Anderson L, Oldridge N, Thompson DR, et al. Exercise-based cardiac rehabilitation for coronary heart disease. J Am Coll Cardiol 2016; 67(1): 1–12.
19.  Craft LL, Perna FM. The benefits of exercise for the clinically depressed. Prim Care Companion J Clin Psychiatry 2004; 6(3): 104–111.
20.  Herring MP, O’Connor PJ, Dishman RK. The effect of exercise training on anxiety symptoms among patients: A systematic review. Arch Intern Med 2010; 170(4): 321-31.
21.  Yaghoubi H. Psychometric properties of the 10 questions Version of the Kessler Psychological Distress Scale (K-10) [in Persian]. Journal of Applied Psychological Research 2016; 6(4): 45-57.
22.  McLain DL. Evidence of the properties of an ambiguity tolerance measure: The Multiple Stimulus Types Ambiguity Tolerance Scale-II (MSTAT-II). Psychol Rep. 2009; 105(3 Pt 1): 975-88.
23.  Ghaziasgar SN, Malekpour M, Abedi A, Faramarzi S. The Impact of Sternberg Success Intelligence Program Training on Increasing Students' Creativity and Tolerance of Ambiguity [in Persian]. Appl Psychol 2022; 16(2): 35-11.
24.  Wildermuth SA. Cognitive behavioral group therapy for adolescents with type I Diabetes. Available from: https://www.proquest.com/openview/947d0b43c1b336f35e80fd564d3fc381/1?pq-origsite=gscholar&cbl=18750. 2008
25.  Aminoff V, Sellén M, Sörliden E, Ludvigsson M, Berg M, Andersson G. Internet-based cognitive behavioral therapy for psychological distress associated with the COVID-19 pandemic: a pilot randomized controlled trial. Front Psychol 2021; 12: 684540.
26.  Hertenstein E, Trinca E, Wunderlin M, Schneider CL, Züst MA, Fehér KD, et al. Cognitive behavioral therapy for insomnia in patients with mental disorders and comorbid insomnia: A systematic review and meta-analysis. Sleep Med Rev 2022; 62: 101597.
27.  Matsumoto K, Hamatani S, Shimizu E. Effectiveness of videoconference-delivered cognitive behavioral therapy for adults with psychiatric disorders: Systematic and meta-analytic review. J Med Internet Res 2021; 23(12): e31293.
28.  da Cunha LL, Feter N, Alt R, Rombaldi AJ. Effects of exercise training on inflammatory, neurotrophic and immunological markers and neurotransmitters in people with depression: A systematic review and meta-analysis. J Affect Disord 2023; 326: 73-82
29.  Dibben G, Faulkner J, Oldridge N, Rees K, Thompson DR, Zwisler AD, Taylor RS. Exercise-based cardiac rehabilitation for coronary heart disease. Cochrane Database Syst Rev 2021; 11(11): CD001800.
30.  Heissel A, Zech P, Rapp MA, Schuch FB, Lawrence JB, Kangas M, Heinzel S. Effects of exercise on depression and anxiety in persons living with HIV: A meta-analysis. J Psychosom Res 2019; 126: 109823.
Volume 44, Issue 853
1st Week, May
May and June 2026
Pages 269-278

  • Receive Date 15 October 2025
  • Accept Date 10 June 2026