The Effect of Golghand (Rosadamacena) on Cognitive Status of Elderly with Mild Cognitive Impairment

Document Type : Original Article(s)

Authors

1 Instructor of Community Health Nursing, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran

2 Assistant Professor of Traditional Medicine, School of Medicine, Social Development and Health Promotion Research Centre, Gonabad University of Medical Sciences, Gonabad, Iran

3 Department of Medical-Surgical Nursing, School of Nursing, Social Development and Health Promotion Research Center, Gonabad University of Medical Sciences, Gonabad, Iran

4 Assistant Professor of Gerontology Department of Gerontology, School of Nursing, Gonabad University of Medical Sciences, Gonabad, Iran

Abstract

Background: Cognitive disorders are one of the most important disorders occurring among the elderly. The present study was designed to evaluate the effect of Golghand consumption on the cognitive status of the elderly people with mild cognitive impairment.
Methods: In this randomized clinical trial study, 70 elderly people aged 60-75 years after completing the demographic, elderly depression and brief cognitive status questionnaires in several stages and random allocation were divided into two groups of intervention and control. The intervention group used Golgand potion once a day for one month. At the end of the post-test questionnaire was completed for both groups. The data were analyzed with independent t and paired t statistical tests with significance level of less than 0.05.
Findings: The mean and standard deviation of the cognitive status score in the experimental group before and after the intervention was 22.57 and 26.17, respectively. The same in score in the control group was 22.65 and 22.66, respectively. The cognitive status scores increased significantly in the intervention group. (P = 0.027), but no significant difference was observed in the control group (P = 0.865). The results also showed a significant increase in the cognitive status scores in the dimensions of orientation, attention, calculation and recall of the questionnaire in the experimental group in the posttest phase (P < 0.05).
Conclusion: According to the present study, Golghand increased cognitive status scores in the intervention group, which indicates the improvement of mild cognitive impairment in the elderly people and the prevention of Alzheimer's diseases.

Keywords

References

  1. Lotfi M, Tagharrobi Z, Sharifi K, Abolhasani J. Diagnostic accuracy of persian version of clinical dementia rating (P-CDR) for early dementia detection in the elderly [in Persian]. J Rafsanjan Univ Med Sci 2015 ;14(4): 283-98.
  2. Moradi M, Mohammadzadeh H, Noori R, Basiri Moghadam K, Sadeghmoghadam L. Effect of a Sleep Hygiene Education Program Using Telephone Follow-up Method on the Sleep Quality of the Elderly [in Persian]. Salmand: Iranian Journal of Ageing 2021; 15(4): 484-95.
  3. Sohrabi M, Zolfaghari P, Mahdizade F, AghayanM, Ghasemian-Aghmashhadi M, Shariati Z, Sohrabi Mb, Zou Alfaghari P, Mahdizadeh F, Aghayan SM, Ghasemian Aghmashhadi M, Shariati Z, et al. Evaluation and comparison of cognitive state and depression in elderlyadmitted in sanitarium with elderly sited in personal home [in Persian]. Knowledge & Health 2008; 3(2): 27-31.
  4. Mirzaei M, Sepahvand E, Sahaf R, Mirzaei S, Pakdel A. The prevalence of cognitive impairment in elderly nursing home residents [in Persian]. J Sabzevar Univ Med Sci 2017; 23(6): 896-901.
  5. Chehrehnegar N, Shams F, Zarshenas S, Kazemi F. Evaluating the reliability of the montreal cognitive assessment test and its agreement with mini mental state examination among healthy elderly [in Persian]. Journal of Research in Rehabilitation Sciences 2011;
    7(5): 674-80.
  6. Amini M, Dowlatshahi B, Dadkhah A, Lotfi M. The effect of memory retention and attention on reducing memory defects in older people depending on dementia Alzheimer [in Persian]. Iranian Journal of Ageing 2013; 8(29): 53-62.
  7. Amusoltani H, Pahlavanzadeh S, Maghsudi Ganjeh J. Vest gating knowledge and attitudes of caregivers of patients affected by mental disorders towards complementary medicine treatments in health centers affiliated to Isfahan University of Medical Sciences in 2014 [in Persian]. Journal of Islamic and Iranian Traditional Medicine 2017; 8(1): 117-23.
  8. Khorasani M. Makhzanoladvieh. Tehran, Iran: Rahe Kamal Publications; 2009. [in Persian].
  9. Meimandi K, Yaghoobi MM. Effects of aqueous and ethanolic extract of Rosa damascena Mill L. against human gastric cancer cells [in Persian]. Iranian Journal of Biology 2015; 28(2): 299-309.
  10. Nazari H, Rashedi V, Mohammadi H, Yousefi M. Relationship between cognitive status and activities of daily living among the elderly of nursing homes [in Persian]. J Kermanshah Univ Med Sci 2015; 18(12): e70733.
  11. Esfandiary E, Karimipour M, Mardani M, Ghanadian M, Alaei HA, Mohammadnejad D, et al. Neuroprotective effects of Rosa damascena extract on learning and memory in a rat model of amyloid-β-induced Alzheimer's disease. Adv Biomed Res 2015; 4: 131.
  12. Esfandiary E, Abdolahi Z, Omranifard V, Ghanadian M, Bagherian-Sararoudi R, Karimipour M, et al. Novel effects of rosa damascena extract on patients with neurocognitive disorder and depression: a clinical trial study. Int J Prev Med 2018; 9: 57.
  13. Mohammadpour A, Sadeghmoghadam L, Shareinia H, Jahani S, Amiri F. Investigating the role of perception of aging and associated factors in death anxiety among the elderly. Clin Interv Aging 2018; 13: 405-10.
  14. Abdolahadi A. Explanation of "Nesyan" in Iranian traditional medicine and study of effects of extract of Nepeta menthoides Boiss and Buhse on cognitive disorders in dementia a double blind clinical trial with placebo [Thesis]. Tehran, Iran: Shahid Beheshti University of Medical Sciences; 2015. [in Persian].
  15. Yu STS, Yu M-L, Brown T, Andrews H. Association between older adults’ functional performance and their scores on the Mini Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). Irish Journal of Occupational Therapy 2018; 46(1): 4-23.
  16. Seydian M, Falah M, Noroozian M, Nejat S, Delavar A, Ghasemzadeh H. Validity of the farsi version of mini-mental state examination [in Persian]. Journal of Medical Council of Iran 2007; 25(4): 408-14.
  17. Ghazanfari F, Hashemi Sh, Sepahvand R. The survey for relation between cognitive status and life quality in older people atarmy retired community in Khorramabad 2011 [in Persian]. Journal of Nurse and Physician Within War 2013; 21-22: 11-17.
  18. Malakuti K, Fatholahi P, Mirabzadeh A, Salavati M, Kahani SH. Standardization of Geriatric Depression Scale (GDS) in Iran [in Persian]. Research in Medicine 2006; 3(4): 361-8.
  19. Boskabady MH, Shafei MN, Saberi Z, Amini S. Pharmacological effects of Rosa damascena. Iran J Basic Med Sci 2011; 14(4): 295-307.
  20. Mohammadpour T, Hosseini M, Naderi A, Karami R, Sadeghnia HR, Soukhtanloo M, et al. Protection against brain tissues oxidative damage as a possible mechanism for the beneficial effects of Rosa damascena hydroalcoholic extract on scopolamine induced memory impairment in rats. Nutr Neurosci 2015; 18(7): 329-36.
  21. Razipour M, Irandoust KH, Taheri M, Effect of aerobic training and Rosa damascena supplement on the memory of obese women. IAHS 2019; 6(3): 136-40.
  22. Awale S, Tohda C, Tezuka Y, Miyazaki M, Kadota S. Protective effects of Rosa damascena and its active constituent on Aβ (25-35)-induced neuritic atrophy. Evid Based Complement Alternat Med 2011; 2011: 131042.
  23. Nayebi N, Khalili N, Kamalinejad M, Emtiazy M. A systematic review of the efficacy and safety of Rosa damascena Mill. with an overview on its phytopharmacological properties. Complement Ther Med 2017; 34: 129-40.
Journal of Isfahan Medical School
Volume 40, Issue 694
2nd Week, January
January and February 2023
Pages 900-907

Files

Share

How to cite

Statistics