1 1 -دانشیار، گروه بیهوشی و مراقبتهای ویژه، دانشکدهی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
2 2 -دستیار، گروه بیهوشی و مراقبتهای ویژه، دانشکدهی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
عنوان مقاله [English]
Background: Due to the need to prevention of postoperative pain after mastoidectomy-tympanoplasty, the
present study was performed to evaluate the preemptive effect of adding morphine to topical lidocaine on
postoperative pain intensity.
Methods: In this double-blind clinical trial study, 80 patients who were candidates for elective mastoidectomytympanoplasty surgery were randomly divided into two groups of 40; the first group underwent local anesthesia
with lidocaine, and the second group underwent local anesthesia with lidocaine with morphine. Patients were
evaluated for hemodynamic parameters, postoperative pain intensity during surgery and recovery and 24 hours
after surgery, and the findings were compared between the two groups.
Findings: Evaluation of patients' pain intensity in recovery and ward showed that at the time of patients'
recovery and two hours after surgery, the intervention group had a lower intensity; but in 12 and 24 hours after
surgery, no significant difference was seen between the two groups. In the intragroup study, pain intensity
significantly reduced in both groups, but the rate of pain reduction in the intervention group was significantly
higher. The trend of changes in hemodynamic parameters during surgery and length stay in recovery was not
significantly different between the two groups.
Conclusion: Addition of morphine to topical lidocaine reduces the postoperative mastoidectomy-tympanoplasty
surgery, while topical use of this drug has no effect on patients' hemodynamics, longer recovery, and extubating time.