نوع مقاله : Original Article(s)
1 استادیار بیهوشی و مراقبتهای ویژه، دانشکده پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
2 دانشجوی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
عنوان مقاله [English]
Background: Recently it is suggested that local injection of tramadol can reduce postoperative pain; but it is controversial whether the intravenous injection is more perfect or subcutaneous. We conducted this study to compare the effect of these methods on postoperative pain.Methods: In a prospective randomized double blind clinical trial study, 75 patients undergoing abdominal surgery were allocated in three groups (n = 25). In group A (subcutaneous), 1.5 mg/kg tramadol was injected subcutaneously and normal saline was injected intravenous in an equal volume of 10 cc; in group B (intravenous) 1.5 mg/kg tramadol was injected intravenous and normal saline was injected subcutaneously in an equal volume of 10 cc;and in group C (control) normal saline was injected subcutaneously and intravenous in an volume of 10 cc. The drugs were injected before incision of surgery in all groups. The severity of postoperative pain after surgery was evaluated by visual analogue scale and the time of first opioid analgesic used and total analgesic dose taken during the postoperative period was recorded.Finding: The total dose of used opioid analgesic was significantly less in subcutaneously injected tramadol group (P < 0.01). The time of the first opioid analgesic consumption was significantly shorter in control group (P < 0.01).Conclusion: According to results of this study, subcutaneous and intravenous injection of tramadol can reduce postoperative pain; subcutaneous injection was more effective, of course. Therefore, subcutaneous tramadol is suggested for control of postoperative pain.