نوع مقاله : مقاله های پژوهشی
1 استادیار، گروه بیماریهای زنان و مامایی، دانشکدهی پزشکی، دانشگاه آزاد اسلامی، واحد نجفآباد، اصفهان، ایران
2 استادیار، گروه بیماریهای زنان و زایمان، دانشکدهی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
3 دانشجوی پزشکی، دانشکدهی پزشکی، دانشگاه آزاد اسلامی، واحد نجف آباد، اصفهان، ایران
4 ماما، دفتر پژوهشی، بیمارستان شهید بهشتی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران
عنوان مقاله [English]
Background: Pregnancy is associated with significant changes in calcium metabolism. During pregnancy, calcium absorption increases through the digestive tube and with high concentration of vitamin D. During pregnancy, vitamin D increases human placental lactogen (HPL), human chorionic gonadotropin (hCG), estrogen and progesterone in a ripe placenta, and its deficiency during pregnancy increases preeclampsia, gestational diabetes, toothache, anemia and bacterial vaginosis in mother, and may cause postpartum seizures, preterm labor (PTL), small for gestational age (SGA), intrauterine growth restriction (IUGR), osteomalacia, infantile rickets, and craniotabes in newborn infants.Methods: This cross-sectional study with a developmental plan was conducted in the first trimester of pregnancy (week 12) on the women referred to Shariati and Alzahra Teaching Hospitals, Isfahan, Iran, in 2012-2013. The study was done in a range of one year and 280 individuals were selected after statistical calculation. Sample collection method was convenient and for each sample, Vit D (OH) 125 was requested during the first trimester of pregnancy. Vitamin D level was measured using E-lex's and Electrochemi-luminescence method (ECLIA), and information related to supplements received by the mothers, general situation of health, use of medicine during pregnancy, pre-pregnancy weight, first trimester weight, maternal age, place of living, receiving vitamin D, maternal hemoglobin level, bacterial vaginosis infection, and toothache in the first trimester were collected through a questionnaire.Findings: Vitamin D level in 280 pregnant women ranged from 1 to 80 nmol/dl. Vitamin D deficiency was examined in four groups of severe (0-20 nmol/dl), moderate (20-40 nmol/dl), and mild deficiency (40-60 nmol/dl) and normal (higher than 60 nmol/dl), and a significant relationship was observed between vitamin D level and associated factors.Conclusion: In this study, anemia, bacterial vaginosis and toothache were more observed in the mothers with low levels of vitamin D.