Journal of Isfahan Medical School

Journal of Isfahan Medical School

The Effect of Work Shift on Fasting Blood Glucose and Lipid Profiles in Workers in Isfahan City, Iran, during the Years 2014-2015

Document Type : Original Article (s)

Authors
Aryan Golabbakhsh 1
Alireza Safaeian 2
Negah Tavakolifard 2
Matin Khanezarrin 1
Seyed Alireza Mortazavi 2
1 Student of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2 Assistant Professor, Department of Community and Family Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
10.22122/jims.v36i467.9202
Abstract
Background: Due to the high prevalence of diabetes and dyslipidemia, which are risk factors for diseases such as metabolic syndrome in today's modern society, especially in the working population, the aim of this study was to determine the effect of shift work on fasting blood glucose and lipid profiles in workers in Isfahan City, Iran, during the years 2014-2015.Methods: In this cross-sectional study, 6983 employees referred to labor centers for periodic examinations were entered according to the inclusion and exclusion criteria. The patients were divided into three groups based on the type of work shift as day, fixed night, and rotate shift workers, and two groups based of type of work as official and non-official workers. The level of blood glucose and lipid profiles [cholesterol, triglyceride, low-density lipoprotein (LDL) and high-density lipoprotein (HDL)] were evaluated and compared between the groups.Findings: There were no significant differences between three groups according to the levels of fasting blood glucose (FBS), triglyceride, and high-density lipoprotein (P > 0.050); but there was a significant difference between the three groups based on the cholesterol and low-density lipoprotein (P < 0.001, for both); so that the cholesterol and low-density lipoprotein levels were higher in day shift worker than others.Conclusion: Based on the results of this study, cholesterol and low-density lipoprotein levels was higher in day shift worker than fixed night and rotate shift workers in high sample sizes of workers in Isfahan City.
Keywords
Shift work
Blood glucose
Cholesterol
Triglycerides
Low-density lipoproteins
High-density lipoproteins
  1. Briancon-Marjollet A, Weiszenstein M, Henri M, Thomas A, Godin-Ribuot D, Polak J. The impact of sleep disorders on glucose metabolism: endocrine and molecular mechanisms. Diabetol Metab Syndr 2015; 7: 25.
  2. Kubo T, Fujino Y, Nakamura T, Kunimoto M, Tabata H, Tsuchiya T, et al. An industry-based cohort study of the association between weight gain and hypertension risk among rotating shift workers. J Occup Environ Med 2013; 55(9): 1041-5.
  3. Gholami-Fesharaki M, Kazemnejad A, Zayeri F, Rowzati M, Sanati J, Akbari H. Multicenter historical cohort study of the relationship between shift work and blood pressure. ARYA Atheroscler 2014; 10(6): 287-91.
  4. Yeom JH, Sim CS, Lee J, Yun SH, Park SJ, Yoo CI, et al. Effect of shift work on hypertension: cross sectional study. Ann Occup Environ Med 2017; 29: 11.
  5. Rosa RR, Colligan MJ. Shift work: Health and performance effects. In: Rom WN, editor. Environmental and occupational medicine. 2nd ed. Boston, MA: Little, Brown and Company; 1992. p. 1173-7.
  6. Brum MC, Filho FF, Schnorr CC, Bottega GB, Rodrigues TC. Shift work and its association with metabolic disorders. Diabetol Metab Syndr 2015; 7: 45.
  7. Ko SB. Night shift work, sleep quality, and obesity. J Lifestyle Med 2013; 3(2): 110-6.
  8. Wehrens SM, Hampton SM, Finn RE, Skene DJ. Effect of total sleep deprivation on postprandial metabolic and insulin responses in shift workers and non-shift workers. J Endocrinol 2010; 206(2): 205-15.
  9. Akbari H, Mirzaei R, Nasrabadi T, Gholami-Fesharaki M. Evaluation of the effect of shift work on serum cholesterol and triglyceride levels. Iran Red Crescent Med J 2015; 17(1): e18723.
  10. Kawabe Y, Nakamura Y, Kikuchi S, Murakami Y, Tanaka T, Takebayashi T, et al. Relationship between shift work and clustering of the metabolic syndrome diagnostic components. J Atheroscler Thromb 2014; 21(7): 703-11.
  11. Yu KH, Yi YH, Kim YJ, Cho BM, Lee SY, Lee JG, et al. Shift work is associated with metabolic syndrome in young female Korean workers. Korean J Fam Med 2017; 38(2): 51-6.
  12. Lo SH, Lin LY, Hwang JS, Chang YY, Liau CS, Wang JD. Working the night shift causes increased vascular stress and delayed recovery in young women. Chronobiol Int 2010; 27(7): 1454-68.
  13. Ha M, Park J. Shiftwork and metabolic risk factors of cardiovascular disease. J Occup Health 2005; 47(2): 89-95.
  14. Alefishat E, Abu FR. Is shift work associated with lipid disturbances and increased insulin resistance? Metab Syndr Relat Disord 2015; 13(9): 400-5.
  15. Ika K, Suzuki E, Mitsuhashi T, Takao S, Doi H. Shift work and diabetes mellitus among male workers in Japan: does the intensity of shift work matter? Acta Med Okayama 2013; 67(1): 25-33.
  16. Chalernvanichakorn T, Sithisarankul P, Hiransuthikul N. Shift work and type 2 diabetic patients' health. J Med Assoc Thai 2008; 91(7): 1093-6.
Journal of Isfahan Medical School
Volume 36, Issue 467 - Serial Number 467
January and February 2018
Pages 77-82

  • Receive Date 20 November 2017
  • Accept Date 06 April 2022