بررسی تغییرات آزمون پوستی توبرکولین در میان کارورزان دانشگاه علوم پزشکی اصفهان پس از گذشت یک سال از شروع دوره‌ی کارورزی در سال 96-1395

نوع مقاله : مقاله های پژوهشی

نویسندگان

1 استادیار، گروه بیماری‌های عفونی، دانشکده‌ی پزشکی و مرکز تحقیقات عفونت‌های بیمارستانی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

2 دانشجوی پزشکی، کمیته‌ی تحقیقات دانشجویی، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

3 استادیار، گروه پزشکی اجتماعی و پزشک خانواده، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

4 دانشیار، گروه پزشکی اجتماعی و پزشک خانواده، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

چکیده

مقدمه: دانشجویان پزشکی به خصوص در مقاطع بالینی در معرض مواجهه با باکتری مایکوباکتریوم توبرکلوزیس هستند و این مسأله، لزوم بررسی دقیق وضعیت مواجهه با بیماری سل در این جمعیت را می‌رساند.روش‌ها: در این مطالعه مقطعی توصیفی تغییرات Tuberculin skin test (TST) درمیان 140 کارورز دانشگاه علوم پزشکی اصفهان در سال 1395 - 1396 بررسی شد. پروتئین تصفیه شده (Purified protein derivative یا PPD)، به داخل جلد در سطح داخلی ساعد تزریق شد. پس از 72 ساعت قطر ایندوراسیون اندازه‌گیری شد. ایندوراسیون 10 میلی‌متر و بیشتر مثبت تلقی شد. یک سال بعد، TST تکرار شد. نتایج TST نوبت اول و نوبت دوم مقایسه گردید و مورد تجزیه و تحلیل قرارگرفت. اطلاعات دموگرافیک پرسیده و ثبت شد.یافته‌ها: 4/46 درصد جمعیت را مردان تشکیل دادند. 8 مورد (7/5 درصد) در نوبت اول و 10 مورد (1/7 درصد) در نوبت دوم TST مثبت داشتند. 2 مورد تغییر (Conversion) PPD یافت شد. میانگین ایندوراسیون نوبت اول 82/2 میلی‌متر و نوبت دوم 17/3 میلی‌متر بود. در آزمون نوبت اول و نوبت دوم، مردان به صورت معنی‌داری TST مثبت داشتند.نتیجه‌گیری: در این مطالعه 2 مورد تغییر PPD یافت شد. با توجه به این که کارورزان در ادامه‌ی دوران تحصیلی و شغلی مواجهه‌ی بیشتری خواهند داشت. این مسأله، ضرورت توجه به استفاده از روش‌های مؤثر جهت کنترل و جلوگیری از انتقال عفونت سل را متذکر می‌سازد.

کلیدواژه‌ها


عنوان مقاله [English]

Evaluation of the Changes in Tuberculin Skin Test (TST) among the Interns in Isfahan University of Medical Sciences (IUMS), Iran, after One Year of Starting Internship during the Years 2016-2017

نویسندگان [English]

  • Kiana Shirani 1
  • Samaneh Rezaee 2
  • Erfan Behzadi 2
  • Zahra Amini 3
  • Parastoo Golshiri 4
1 Assistant Professor, Department of Infectious Diseases, School of Medicine AND Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2 Student of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Assistant Professor, Department of Community Medicine and Family Physician, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
4 Associate Professor, Department of Community Medicine and Family Physician, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده [English]

Background: Medical students, especially whom enter to clinical courses, are in high exposure of Mycobacterium tuberculosis responsible for tuberculosis (TB). This emphasizes the need to evaluate the condition of exposure to tuberculosis in this population.Methods: In this cross-sectional descriptive study, changes in tuberculin skin test (TST) was evaluated among 140 interns in Isfahan University of Medical Sciences (IUMS), Iran, during the years 2016-2017. Purified protein derivative (PPD) was injected into the medial side of forearm. After 72 hours, the diameter of induration was measured. 10 mm of induration and higher was considered as positive. 1 year later, the tuberculin skin test was repeated. The results from the first and second tuberculin skin tests were compared and analyzed. Demographic information was recorded.Findings: 46.4% of examined population were men. In first tuberculin skin test, 8 cases (5.7%), and in second test, 10 cases (7.1%) were positive. 2 cases of test conversion were found. Mean induration size among all interns was 2.82 and 3.17 mm in first and second tuberculin skin tests, respectively. In both tests, men had significantly more positive results.Conclusion: In this study, 2 test conversion cases were found. As these interns will have more exposure in their educational and professional future, it needs to perform useful plans to control and prevent transmission of tuberculosis.

کلیدواژه‌ها [English]

  • Tuberculosis
  • Tuberculin test
  • Medical student
  • Iran
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