تأثیر فعالیت ورزشی اینتروال با شدت بالا بر میزان آسیب بافت عضله در رت‌های نر ویستار

نوع مقاله : مقاله های پژوهشی

نویسندگان

1 کارشناسی ارشد، گروه فیزیولوژی ورزشی، واحد ایلام، دانشگاه آزاد اسلامی، ایلام، ایران

2 استادیار، گروه فیزیولوژی ورزشی، واحد ایلام، دانشگاه آزاد اسلامی، ایلام، ایران

3 دانشیار، گروه آسیب‌شناسی، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی ایلام، ایلام، ایران

چکیده

مقاله پژوهشی




مقدمه: تمرینات اینتروال با شدت بالا (High-intensity intermittent exercise) HIIE یک برنامه‌ی تمرینی است که به طور فزاینده‌ای، محبوب شده است و با جلسات کوتاه نتایج مثبتی را ارائه می‌دهد. هدف از این مطالعه، ارزیابی تأثیر یک جلسه HIIE بر آسیب و التهاب عضلانی بود.
روش‌ها: 25 رت نر ویستار به صورت تصادفی به سه گروه شاهد (تعداد 8)، گروه تمرین HIIE که یک ساعت (HIIE-1h) (تعداد 8) و 24 ساعت (HIIE-24h) (تعداد 9)، تقسیم و سپس بعد از تمرین قربانی شدند. حیوانات گروه HIIE تحت یک فعالیت ورزشی اینتروال با شدت بالا (VO2max 100-85 درصد) که شامل
10 ست تمرین- ریکاوری بود، قرار گرفتند. هر ست شامل یک دقیقه دویدن بر روی تردمیل با شیب 10 درجه با سرعت 28 متر بر دقیقه و ریکاوری دو دقیقه دویدن بر روی تردمیل بدون شیب و با سرعت 10 متر بر دقیقه بود. سطح اینترلوکین‌های IL-6 و IL-8 در سرم و میزان التهاب و آسیب عضلانی مورد ارزیابی قرار گرفت. از آزمون تحلیل واریانس برای تجزیه و تحلیل داده‌ها استفاده شد.
یافته‌ها: سطح IL-6 و IL-8 سرم در گروه‌های HIIE-1h و HIIE-24h نسبت به گروه شاهد افزایش معنی‌داری را نشان داد (0/05 > P). همچنین، نتایج پاتولوژی نشان داد که التهاب و واپاشی تارهای عضلانی در عضله‌ی ساقی قدامی در گروه HIIE-24h و HIIE-1h نسبت به گروه شاهد، معنی‌دار بود.
نتیجه‌گیری: یک جلسه HIIE منجر به التهاب و واپاشی در تارهای عضله‌ی اسکلتی می‌شود. سطح IL-6 و IL-8 در سرم نیز افزایش معنی‌داری را نشان داد که با آسیب و التهاب عضله می‌تواند در ارتباط باشد.

کلیدواژه‌ها

عنوان مقاله [English]

The Effect of High-Intensity Intermittent Exercise on Muscle Damage in Male Wistar Rat

نویسندگان [English]

  • Fatemeh Movahedi 1
  • Maryam Abbasi 2
  • Mohamadreza Hafezi Ahmadi 3
1 MSc, Department of Sport Physiology, Ilam Branch, Islamic Azad University, Ilam, Iran
2 Assistant Professor, Department of Sport Physiology, Ilam Branch. Islamic Azad University, Ilam, Iran
3 Associate Professor, Department of Pathology, School of Medicine, Ilam University of Medical Sciences, Ilam, Iran
چکیده [English]

Background: High-intensity intermittent exercise (HIIE) is an increasingly popular exercise program that provides positive results with short sessions. The aim of this study was to evaluate the effect of one session of HIIE on muscle damage and inflammation.
Methods: Twenty-five male Wistar rats were randomly divided into three groups: control (Control, n = 8), HIIE, which were euthanized one hour after training (HIIE-1h, n = 8), and 24 hours after training (HIIE-24h, n = 9). HIIE group was subjected to a high-intensity interval exercise (VO2max 85-100%) that included ten exercise-recovery sets which was composed of 10 bouts of high intensity exercise of 1 min each (85-100% of VO2max), at 28 m/min, 10° inclinations on the treadmill interspersed by 2 min of active recovery, at 10 m/min, with no inclination. Serum IL-6 and IL-8 levels and the skeletal muscle inflammation and damage were assessed. Analysis of variance at 95% confidence level was used to analyze the data.
Findings: Serum IL-6 and IL-8 levels in the HIIE-1h and HIIE-24h groups showed a significant increase compared to the control group. Also, the pathology results showed that the inflammation and rhabdomyolysis of muscle fibers in the tibialis anterior muscle in the HIIE-24h and HIIE-1h groups were significant compared to the control group.
Conclusion: An HIIE session leads to inflammation and rhabdomyolysis in skeletal muscle. Serum IL-6 and
IL-8 levels also showed a significant increase that could be associated with muscle damage and inflammation.

کلیدواژه‌ها [English]

  • High-intensity intermittent exercise
  • Cytokines
  • Rhabdomyolysis

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مجله دانشکده پزشکی اصفهان
دوره 40، شماره 682
هفته 2 مهرماه
مهر و آبان 1401
صفحه 593-601

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سابقه مقاله

  • تاریخ دریافت: 24 مرداد 1401
  • تاریخ پذیرش: 10 مهر 1401

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