نوع مقاله : مقاله های پژوهشی
1 کارشناسی ارشد، گروه فیزیولوژی ورزشی، واحد ایلام، دانشگاه آزاد اسلامی، ایلام، ایران
2 استادیار، گروه فیزیولوژی ورزشی، واحد ایلام، دانشگاه آزاد اسلامی، ایلام، ایران
3 دانشیار، گروه آسیبشناسی، دانشکدهی پزشکی، دانشگاه علوم پزشکی ایلام، ایلام، ایران
عنوان مقاله [English]
Background: High-intensity intermittent exercise (HIIE) is an increasingly popular exercise program that provides positive results with short sessions. The aim of this study was to evaluate the effect of one session of HIIE on muscle damage and inflammation.
Methods: Twenty-five male Wistar rats were randomly divided into three groups: control (Control, n = 8), HIIE, which were euthanized one hour after training (HIIE-1h, n = 8), and 24 hours after training (HIIE-24h, n = 9). HIIE group was subjected to a high-intensity interval exercise (VO2max 85-100%) that included ten exercise-recovery sets which was composed of 10 bouts of high intensity exercise of 1 min each (85-100% of VO2max), at 28 m/min, 10° inclinations on the treadmill interspersed by 2 min of active recovery, at 10 m/min, with no inclination. Serum IL-6 and IL-8 levels and the skeletal muscle inflammation and damage were assessed. Analysis of variance at 95% confidence level was used to analyze the data.
Findings: Serum IL-6 and IL-8 levels in the HIIE-1h and HIIE-24h groups showed a significant increase compared to the control group. Also, the pathology results showed that the inflammation and rhabdomyolysis of muscle fibers in the tibialis anterior muscle in the HIIE-24h and HIIE-1h groups were significant compared to the control group.
Conclusion: An HIIE session leads to inflammation and rhabdomyolysis in skeletal muscle. Serum IL-6 and
IL-8 levels also showed a significant increase that could be associated with muscle damage and inflammation.