مروری بر پیامدهای بارداری در زنان باردار واکسینه شده علیه کووید-19

نوع مقاله : Review Article

نویسندگان

1 دانشجوی دکتری تخصصی بهداشت باروری، کمیته‌ی تحقیقات دانشجویی، مرکز تحقیقات مامایی و بهداشت باروری، دانشکده‌ی پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران

2 دانشیار، مرکز تحقیقات مامایی و بهداشت باروری، گروه مامایی و بهداشت باروری، دانشکده‌ی پرستاری و مامایی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران

چکیده

مقاله مروری




مقدمه: شواهد نشان داده است، پاندمی کوید-19 می‌تواند عوارض و عواقب ناخوشایندی را برای مادر باردار و جنین داشته باشد. لذا واکسیناسیون مادران باردار جهت ایمن ساختن این گروه نیز انجام شد. جهت تجمیع دانش موجود در مورد اثربخشی و پیامدهای بارداری در زنانی که این واکسیناسیون را انجام دادند، این مطالعه طراحی و اجرا گردید.
روش‌ها: در این مطالعه‌ی مروری سیستماتیک، همه‌ی مطالعات منتشر شده تا تاریخ 24/2/2022 وارد مطالعه شدند. جستجوی مطالعات در پایگاه اطلاعاتی Embase، Scopus، Web of Science، PubMed و با استفاده از کلمات کلیدی Pregnancy، COVID-19 virus vaccines، Pregnancy complications،
Fetal outcome انجام شد. دو پژوهشگر به طور مستقل مقالات را جهت ارزیابی کیفیت (با استفاده از ابزار Newcastle-Ottawa) و استخراج یافته‌های اصلی آن‌ها مورد بررسی قرار دادند.
یافته‌ها: در این مطالعه‌ی مروری، 10 مطالعه مطابق با معیارهای ورود با 40522 زن باردار که واکسن کووید-19 دریافت کرده بودند، وارد شدند. بروز عوارض مادری پس از واکسیناسیون، فوق‌العاده کم بود. در بین زنان باردار، بر اساس اینکه واکسن در سه ماهه‌ی اول، دوم یا سوم بارداری تزریق شده باشد، تفاوت معنی‌داری در میزان عوارض مادری وجود نداشت. واکسیناسیون کووید-19 در دوران بارداری با افزایش عوارض بارداری یا زایمان مرتبط نبود.
نتیجه‌گیری: با توجه به این که ایمنی و اثربخشی واکسن کووید-19 عوامل مهمی در دستیابی به مصونیت جمعیت هستند. پذیرش گسترده‌تر واکسن‌ها برای دستیابی به پوشش ایمن‌سازی کافی، ضروری است. ارائه‌دهندگان مراقبت‌های بهداشتی می‌توانند از داده‌های موجود برای آموزش و توانمندسازی افراد باردار برای تصمیم‌گیری آگاهانه استفاده کنند.

کلیدواژه‌ها

عنوان مقاله [English]

A Review of Pregnancy Outcomes in Pregnant Women Vaccinated Against COVID-19

نویسندگان [English]

  • Fereshte Ghahremani 1
  • Alizadeh leila 1
  • Marjan Havaei 1
  • Elnaz Haji Rafiei 1
  • Seyedeh Maryam Khalili 1
  • Gity Ozgoly 1
  • Mahrokh Dolatian 2
1 PhD Student of Reproductive Health, Students Research Committee, Midwifery and Reproductive Health Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2 Associate Professor, Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
چکیده [English]

Background: Evidence has shown that the COVID-19 pandemic can have unpleasant side effects for pregnant women and fetuses. Therefore, vaccination of pregnant women was performed to make this group safe. In order to consolidate the existing knowledge about the effectiveness and consequences of pregnancy in women who underwent this vaccination, this study was designed and implemented.
Methods: In this systematic review study, all published studies up to 24.2.2022 were included in the study. The studies were searched in the databases of Embase, PubMed, Web of Science, Scopus using the keywords Pregnancy, COVID-19 Virus Vaccines, Pregnancy Complications and fetal outcome. The two researchers independently reviewed the articles for quality assessment (using the Newcastle-Ottawa tool) and extracted their main findings.
Findings: In this review study, 10 studies were included in accordance with the inclusion criteria with
40522 pregnant women who received the COVID-19 vaccine. The incidence of maternal complications after vaccination was extremely low. Among pregnant women, there was no significant difference in maternal complications based on whether the vaccine was given in the first, second or third trimester of pregnancy. Covid-19 vaccination during pregnancy was not associated with an increase in pregnancy complications or delivery.
Conclusion: Considering that the safety and efficacy of COVID-19 vaccine are important factors in achieving population immunity, more acceptance of vaccines is essential to achieve adequate immunization coverage. Health care providers can use the available data to educate and empower pregnant women to make informed decisions.

کلیدواژه‌ها [English]

  • Adverse effects
  • COVID-19 vaccines
  • Efficiency
  • Pregnancy outcome
  • Vaccination

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مجله دانشکده پزشکی اصفهان
دوره 40، شماره 687
هفته 3 آبان ماه
مهر و آبان 1401
صفحه 718-728

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  • تاریخ دریافت: 0-321 فروردین 781
  • تاریخ پذیرش: 0-230 فروردین 781

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