Journal of Isfahan Medical School

Journal of Isfahan Medical School

The Seroprevalence of Anti-Toxoplasma Gondii IgG and IgM Antibodies in Serum Samples Referred to Educational Hospitals of Abadan

Document Type : Original Article(s)

Authors
Shahrzad Soltani 1
Hadi Moghaddam 2
Maghsoudi Fatemeh 3
Sanaz Tavakoli 4
1 Assistant Professor, Department of Medical Parasitology School of Medicine, Abadan University of Medical Sciences, Abadan, Iran
2 Medical Student, School of Medicine, Abadan University of Medical Sciences, Abadan, Iran
3 MSc, Department of Public Health, School of Health, Abadan University of Medical Sciences, Abadan, Iran
4 PhD Candidate of Medical Parasitology, Department of Parasitology and Mycology, School of Medicine, Isfahan University of
10.48305/jims.v40.i692.0843
Abstract
Background: Toxoplasma gondii is an obligate apicomplexan parasite and it is stated that one-third of the world population are seropositive for the antibodies against the parasite. The purpose of this study is to determine the sero-prevalence of anti-toxoplasma gondii IgG and IgM antibodies in serums of patients referred to educational hospitals of Abadan, southwest Iran.
Methods: In this cross sectional study, 252 serum samples referred to Taleghani and Beheshti hospitals were investigated in 2022. The serum of patients were evaluated for anti-toxoplasma gondii IgG and IgM antibodies using ELISA. A questionnaire containing demographic information and risk factors related to Toxoplasma gondii infection was completed by each patient. P value under 0.05 was considered as statistically significant.
Findings: Among 252 evaluated serums, 100 cases (39.7%) and 7 cases (2.8%) had IgG and IgM antibodies against Toxoplasma gondii, the difference was statistically significant. The sero-prevalence of anti-toxoplasma gondii IgG and IgM antibodies were significantly higher in patients’ serums who had contact with cats and dogs and who consumed under cooked meat.
Conclusion: Considering the relatively high prevalence of anti-toxoplasma gondii immunoglobulin in the serum of patients referred to Abadan hospitals, more attention should be paid for the prevention, diagnosis and treatment of this high-risk group.
Keywords
Enzyme-linked immunosorbent assay
IgM
IgG
Sero-epidemiologic studies
Toxoplasma
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Journal of Isfahan Medical School
Volume 40, Issue 692
4th Week, December
November and December 2022
Pages 843-850