Background: This study investigated the impact of type 1 diabetes on antibody levels in individuals with diabetic nephropathy and the consequent increased risk of toxoplasmosis. The research compared the titers of anti-Toxoplasma antibodies in diabetic patients with those in a healthy control group, considering the impaired immune function in these patients.
Methods: A study conducted in Zabol City from October 2019 to January 2021 involved 45 individuals with Type 1 Diabetes and 45 healthy participants. The ELISA method was used to measure IgM and IgG anti-Toxoplasma antibodies.
Findings: In the diabetic group, twenty samples were positive for IgG antibodies, and five were positive for both IgG and IgM antibodies. In the Control Group, all twenty samples were positive for IgG antibodies, and none were positive for IgM antibodies.
Conclusion: Although there is no significant link between type 1 diabetes and IgG, a statistical association was found between IgM and a higher risk of toxoplasmosis infection. The existence of confounding factors necessitates further investigation to fully understand the link between type 1 diabetes and toxoplasmosis in this domain.