مجله دانشکده پزشکی اصفهان

مجله دانشکده پزشکی اصفهان

تأثیر تمرینات ورزشی بر سطوح آدیپونکتین در بیماران دیابتی نوع 2 بر اساس تفکیک جنسیت: یک مرور نظام‌مند و فراتحلیل

نوع مقاله : مقاله مروری

نویسندگان
عارف مهدی پور 1
سید مرتضی طیبی 2
احسان امیری 1
محمود غفاری 3
زهرا امامی 1
1 دانشجوی دکتری، گروه فیزیولوژی ورزشی، دانشکده‌ی علوم انسانی و اجتماعی، دانشگاه کردستان، سنندج، ایران
2 دانشیار، گروه فیزیولوژی ورزشی، دانشکده‌ی تربیت بدنی و علوم ورزشی، دانشگاه علامه طباطبائی، تهران، ایران
3 کارشناسی ارشد، گروه فیزیولوژی ورزشی، دانشکده‌ی تربیت بدنی و علوم ورزشی، دانشگاه علامه طباطبائی، تهران، ایران
10.48305/jims.v43.i826.0956
چکیده
مقاله مروری




مقدمه: هدف از این مطالعه‌ی مروری نظام‌مند و فراتحلیل، بررسی تأثیر فعالیت ورزشی بر سطوح آدیپونکتین در بیماران مبتلا به دیابت نوع 2 بر اساس تفکیک جنسیت بود.
روش‌ها: این مطالعه‌ی مرور نظام‌مند و فراتحلیل بر اساس PRISMA و دستورالعمل‌های جنسیت و برابری جنسیتی در تحقیقات (SAGER) انجام شد. در این مطالعه به منظور استخراج اطلاعات مربوط به مطالعه، پایگاه‌های اطلاعاتی معتبر PubMed، Web of Science، Scopus، Google Scholar و پایگاه فارسی زبان SID توسط دو محقق مستقل برای یافتن مطالعاتی که تأثیر تمرینات ورزشی را بر سطوح آدیپونکتین در افراد مبتلا به دیابت نوع دو بررسی کرده بودند، مورد جستجو قرار گرفتند. اثرات تلفیقی مداخلات به عنوان تفاوت میانگین استاندارد شده (SMD) با مدل اثرات تصادفی ارزیابی شدند. تست حساسیت برای ارزیابی تحت تاثیر بودن فراتحلیل با مطالعه خاصی، مورد استفاده قرار گرفت.
یافته‌ها: با توجه به یافته‌های این فراتحلیل، فعالیت ورزشی تأثیر معنی‌داری بر سطوح آدیپونکتین در زنان دیابتی نوع 2 داشت (0/01 > P ,(0/35- تا 1/18- :95 درصد فاصله اطمینان) 0/77- = SMD) ولی در تجزیه و تحلیل داده مربوط به مردان دیابتی نوع 2 تأثیر معنی‌داری مشاهده نشد (0/09 = P ,(0/06- تا 0/77- :95 درصد فاصله اطمینان) 0/35- = SMD).
نتیجه‌گیری: فعالیت ورزشی می‌تواند به طور قابل توجه‌ای از طریق کنترل سطوح پلاسمایی آدیپونکتین، به عنوان راهبردی غیردارویی در بهبود عوارض ناشی از بیماری در زنان مبتلا به دیابت نوع 2 ایفای نقش کند.

تازه های تحقیق

عارف مهدی پور:  Google Scholar 

سید مرتضی طیبی:  Google Scholar 

احسان امیری:  Google Scholar 

کلیدواژه‌ها
آدیپوسیتوکین
دیابت نوع 2
فعالیت ورزشی
ورزش هوازی
تمرینات مقاومتی

عنوان مقاله English

The Effect of Exercise Training on Adiponectin in Type 2 Diabetic Patients Based on Gender: A Systematic Review and Meta-Analysis

نویسندگان English

Aref Mehdipour 1
Seyed Morteza Tayebi 2
Ehsan Amiri 1
Mahmoud Ghaffari 3
Zahra Emami 1
1 PhD. Candidate, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran
2 Associate Professor, Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, Allameh Tabataba'i University, Tehran, Iran
3 MSc, Department of Exercise Physiology, Faculty of Humanities and Social Sciences, University of Kurdistan, Sanandaj, Iran
چکیده English

Background: The purpose of this systematic review and meta-analysis is to examine the effect of exercise training on adiponectin levels in patients with type 2 diabetes mellitus (T2DM) based on gender.
Methods: This systematic review and meta-analysis were conducted based on the PRISMA guidelines and the Sex and Gender Equity in Research (SAGER). To extract relevant information for the study, reputable databases including PubMed, Web of Science, Scopus, Google Scholar, and the Persian language database (SID) were searched by two independent researchers to find studies that had examined the effect of exercise on adiponectin levels in individuals with T2DM. The combined effects of interventions were assessed as standardized mean differences (SMD) using a random-effects model. Sensitivity analysis was performed to evaluate the influence of specific studies on the overall results.
Findings: According to the findings of this meta-analysis, exercise training had a significant effect on adiponectin levels in women with T2DM (SMD = -0.77, 95% CI: (-0.35 to -1.18), P < 0.01), but no significant effect was observed in the analysis of data related to men with T2DM (SMD = -0.35, 95% CI: -0.06 to -0.77, P = 0.09).
Conclusion: Based on the results of this meta-analysis, exercise training can effectively play a role by controlling plasma levels of adiponectin as a non-pharmacological strategy in improving the complications caused by the disease in women with T2DM.

کلیدواژه‌ها English

Adipocytokine
Type 2 diabetes
Physical activity
Aerobic exercise
Resistance training
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مجله دانشکده پزشکی اصفهان
دوره 43، شماره 826
هفته 2، مهر
مهر و آبان 1404
صفحه 956-968

  • تاریخ دریافت 30 اردیبهشت 1403
  • تاریخ پذیرش 21 خرداد 1404