نوع مقاله : Original Article(s)
عنوان مقاله English
نویسندگان English
Background: Postoperative shivering is a frequent and distressing complication following spinal anesthesia in cesarean sections, with significant physiological consequences. Meperidine has been proposed as an effective prophylactic agent, but the optimal route of administration remains under investigation/the aim of this study was to compare the prophylactic efficacy and safety of low-dose intrathecal meperidine versus intravenous meperidine and placebo for the prevention of shivering in elective cesarean sections under spinal anesthesia.
Methods: In this randomized, double-blind, placebo-controlled trial, 151 parturients (ASA physical status II, aged 18–47) scheduled for elective cesarean section under spinal anesthesia were allocated into three groups: the Intrathecal Meperidine group (MEP-IT, n=49; receiving 12/5"-" 15" mg" hyperbaric bupivacaine plus 0/1" mg/kg" intrathecal meperidine, and 1" mL" IV normal saline), the Intravenous Meperidine group (MEP-IV, n=51; receiving bupivacaine intrathecally plus 0/3" mg/kg" IV meperidine), and the Control group (n=51; receiving bupivacaine intrathecally plus IV normal saline)/ Shivering incidence, severity (graded 0–4), hemodynamic parameters, and core temperature were monitored for 60 minutes.
کلیدواژهها English
