بررسی خصوصیات اپتیکی، فیزیکی و کوانتومی نانوذرات طلا و کاربردهای آن در تشخیص و درمان سرطان‌ها

نوع مقاله : مقاله مروری

نویسندگان

1 دانشجوی دکتری، گروه فیزیک پزشکی، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی جندی شاپور اهواز، اهواز، ایران

2 استاد، گروه فیزیک پزشکی، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

چکیده

نانوذرات طلا از پتانسیل بالایی برای تشخیص، بهبود و درمان سرطان برخوردار هستند. زیست پذیری بالا، تجمع انتخابی در سلول‌های سرطانی و سمیت پایین از جمله مزیت‌های این ذرات می‌باشد. تحقیقات قابل توجهی به استفاده از نانوذرات طلا به عنوان عامل افزایش دهنده‌ی کنتراست تصویربرداری رامان و تصویربرداری پرتو ایکس و نیز عامل گرمادرمانی و افزایش دهنده‌ی حساسیت پرتویی تومور پرداخته است. در مطالعه‌ی حاضر، خصوصیات اپتیکی، فیزیکی و کوانتومی نانوذرات طلا و همچنین چگونگی استفاده از این خصوصیات در زمینه‌های تشخیصی و درمانی سرطان مورد بحث و بررسی قرار گرفته است.

کلیدواژه‌ها

عنوان مقاله [English]

Optical, Physical and Quantum Properties of Gold Nanoparticles and its Applications in Diagnosis and Treatment of Cancers

نویسندگان [English]

  • Zahra Arab-Bafrani 1
  • Daryoush Shahbazi-Gahrouei 2
1 PhD Candidate, Department of Medical Physics, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
2 Professor, Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
چکیده [English]

Today, it has been shown that gold nanoparticles have great potential to improve diagnosis and treatment of cancers. The special advantages of gold nanoparticle are high biocompatibility, selective accumulating at cancer cells and low toxicity. Considerable research is underway into the use of gold nanoparticle as contrast agent in Raman spectroscopy, X-ray imaging, photo-thermal agents and radiosensitizers. In this study, optical and physical and quantum properties of gold nanoparticle are discussed. Subsequently, medical application of gold nanoparticle, as a dual use in diagnosis and treatment of cancers, are considered.

کلیدواژه‌ها [English]

  • Gold nanoparticles
  • Medical application
  • Physical
  • Optical
  • Quantum

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مجله دانشکده پزشکی اصفهان
دوره 33، شماره 323 - شماره پیاپی 323
فروردین و اردیبهشت 1394
صفحه 160-170

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سابقه مقاله

  • تاریخ دریافت: 22 مهر 1393
  • تاریخ بازنگری: 31 فروردین 1403
  • تاریخ پذیرش: 17 فروردین 1401

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