نوع مقاله : مقاله های پژوهشی
1 دانشجوی پزشکی، دانشکدهی پزشکی، دانشگاه آزاد اسلامی، واحد نجفآباد، اصفهان، ایران
2 گروه جراحی اعصاب، دانشکدهی پزشکی، دانشگاه آزاد اسلامی، واحد نجفآباد، اصفهان، ایران
3 استادیار، گروه بهداشت، دانشکدهی پزشکی، دانشگاه آزاد اسلامی، واحد نجفآباد، اصفهان، ایران
عنوان مقاله [English]
Background: Epidemiological studies have reported a high prevalence of vitamin D deficiency in different regions of the world, including Iran. This study aimed to determine the prevalence of vitamin D deficiency in patients with degenerative diseases of spine, which underwent spine surgery, and to assess the relationship between vitamin D deficiency and age, sex, obesity, smoking, and taking supplements.Methods: In this cross-sectional and non-interventional study, the serum level of 25(OH)D was determined via electrochemiluminescence immunoassay method. Other variables were firmed through relevant questionnaires. To analyze the data, univariate and multiple regression analysis were used.Findings: 110 patients enrolled the study. The mean serum level of 25(OH) D was 27.45 ± 18.75 ng/ml. 44.5% of patients showed vitamin D deficiency [25(OH)D < 20 ng/ml], and in 17.3% of the patients, the serum level of 25(OH)D was insufficient [20 ng/ml ≤ 25(OH)D < 30 ng/ml]. In group with the history of taking supplements, the prevalence of hypovitaminosis D was 47.6%. The prevalence of vitamin D deficiency was significantly higher in younger age group (20-39 years old) (P = 0.003) and the ones without the history of taking supplements (P < 0.001). Compared to men, women showed significantly higher levels of vitamin D (P = 0.030), as well as higher levels of consumption of vitamin D supplements. There was no significant correlation between other variables.Conclusion: A high prevalence of vitamin D deficiency was seen in patients with degenerative diseases of spine, even in patients treated with vitamin supplements. On the other hand, considering the risk factors alone seems not to be sufficient in determining the likelihood of deficiency. So, it is recommended to screen vitamin D deficiency via measuring the serum level of 25(OH)D and consequently to treat properly and sufficiently patients with degenerative diseases of spine, especially patients with surgical interventions.