مجله دانشکده پزشکی اصفهان

مجله دانشکده پزشکی اصفهان

تأثیر 12 هفته تمرین تناوبی بر فشار خون و رگ‌گشایی ناشی از جریان در مردان میانسال مبتلا به پرفشاری خون

نوع مقاله : مقاله های پژوهشی

نویسندگان
میثم شعبانی‌نیا 1
فرشته شهیدی 2
حمید رجبی 3
ایرج نظری 4
1 دانشجوی دکتری، گروه فیزیولوژی ورزشی، دانشکده‌ی تربیت بدنی و علوم ورزشی، دانشگاه تربیت دبیر شهید رجایی تهران، تهران، ایران
2 استادیار، گروه فیزولوژی ورزشی، دانشکده‌ی تربیت بدنی و علوم ورزشی، دانشگاه تربیت دبیر شهید رجایی تهران، تهران، ایران
3 دانشیار، گروه فیزولوژی ورزشی، دانشکده‌ی تربیت بدنی و علوم ورزشی، دانشگاه خوارزمی تهران، تهران، ایران
4 استادیار، گروه جراحی داخلی، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی جندی‌شاپور اهواز، اهواز، ایران
چکیده
مقدمه: رگ‌گشایی ناشی از جریان (Flow-mediated dilation یا FMD) در شرایط پرفشاری خون مختل می‌شود و به نظر می‌رسد تمرین ورزشی می‌تواند آن را بهبود بخشد. پژوهش حاضر، با هدف مقایسه‌ی FMD بین افراد سالم و مبتلا به پرفشاری خون و بررسی تأثیر 12 هفته تمرین هوازی تناوبی بر آن انجام شد.روش‌ها: در این پژوهش نیمه‌تجربی، 12 مرد میانسال سالم و 24 مرد میانسال مبتلا به پرفشاری خون با سن 80/2 ± 66/49 سال، قد 66/4 ± 16/174 سانتی‌متر و وزن 65/12 ± 08/81 کیلوگرم و انتخاب شدند. افراد بیمار در دو گروه 12 نفره‌ی شاهد با سن 53/2 ± 08/52 سال، قد 81/5 ± 75/173 سانتی‌متر و وزن 26/8 ± 08/80 کیلوگرم و تمرین تناوبی با سن 91/2 ± 50/50 سال، قد 69/4 ± 40/173 و وزن 60/13 ± 20/85 کیلوگرم قرار گرفتند. تمرین شامل 12 هفته دویدن تناوبی با شدت 50 و 80 درصد ضربان قلب ذخیره به مدت 2 و 1 دقیقه و سه جلسه در هفته روی تردمیل برای 12 دقیقه بود که تا 6 هفته هر هفته 3 دقیقه و پس از آن هر 2 هفته، 3 دقیقه به زمان آن اضافه شد؛ به گونه‌ای که زمان تمرین در 2 هفته‌ی آخر به 36 دقیقه رسید. فشار خون و FMD قبل و بعد از دوره‌ی تمرین اندازه‌گیری شد. طبیعی بودن توزیع داده‌ها با آزمون Shapiro-Wilk سنجیده شد.یافته‌ها: نتایج آزمون Independent t نشان داد که FMD در بیماران از افراد سالم کمتر بود (469/4 = t و 001/0 > P). همچنین، آزمون‌های One-way ANOVA و Repeated measures ANOVA نشان داد که تمرین تناوبی باعث کاهش معنی‌دار فشار خون سیستول (059/7 = F و 015/0 = P) و افزایش FMD (63/13 = F و 001/0 = P) می‌شود.نتیجه‌گیری: به نظر می‌رسد رگ‌گشایی ناشی از جریان، در بیماران مبتلا به پرفشاری خون مختل می‌شود و این افراد برای کاهش فشار خون و بهبود عملکرد اندوتلیومی، می‌توانند تمرین هوازی تناوبی انجام دهند.واژگان کلیدی: فشار خون، جریان خون ناحیه‌ای، تمرین
کلیدواژه‌ها
فشار خون
جریان خون ناحیه‌ای
تمرین هوازی

عنوان مقاله English

Effect of 12-Weeks Interval Aerobic Training on Blood Pressure and Flow-Mediated Dilation in Middle-Aged Men with Hypertension

نویسندگان English

Maysam Shabaaninia 1
Fereshteh Shahidi 2
Hamid Rajabi 3
Iraj Nazari 4
1 PhD Candidate, Department of Sport Physiology, School of Physical Educattion and Sport Sciences, Shahid Rajaee Teacher Treaining University of Tehran, Tehran, Iran
2 Assistant Professor, Department of Sport Physiology, School of Physical Educattion and Sport Sciences, Shahid Rajaee Teacher Treaining University of Tehran, Tehran, Iran, Tehran, Iran
3 Associate Professor, Department of Sport Physiology, School of Physical Educattion and Sport Sciences, Kharazmi University, Tehran, Iran
4 Assistant Professor, Department of General Surgery, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
چکیده English

Background: Flow-mediated dilation (FMD) in terms of blood pressure is impaired and it seems that exercise training can improve it. The present study intended to compare flow-mediated dilation in patients with hypertension and normotensive people and examine the effect of exercise on it.Methods: In this semi-experimental study, 12 normotensive and 24 hypertensive middle-aged men (age: 49.66 ± 2.80 years, height: 174.16 ± 4.66 cm, weight: 81.08 ± 12.65 kg) were selected using convenience sampling method. Patients were randomly divided to equal groups; 12 for control (age: 52.08 ± 2.53 years, height: 173.75 ± 5.81 cm, weight: 80.08 ± 8.26 kg) and 12 for interval aerobic training (age: 50.50 ± 2.91 years, height: 173.4 ± 4.69 cm, weight: 85.2 ± 13.6 kg). The training included 12 weeks of treadmill interval aerobic running with 50 and 80% heart rate reserve for 2 and 1 minute, respectively, three times a week for totally 12 minutes each session. Each week, 3 minutes to 6th week and then, every two weeks, 3 minutes added to the training time. So that, training in the last two weeks was 36 minutes. Blood pressure and flow-mediated dilation were taken before and after the training period. The distribution normality of data was assessed using Shapiro-Wilk test.Findings: Independent t-test showed that flow-mediated dilation was lower in patients than in normotensive subjects (t = 4.469, P < 0.001). The analysis of variance with repeated measures showed that the training significantly reduced systolic blood pressure (F = 7.059, P = 0.015) and increased flow-mediated dilation (F = 13.63, P = 0.001).Conclusion: It seems that, flow-mediated dilation in patients with hypertension is impaired and these patients can do aerobic interval training to relieve pressure and improve endothelial function.

کلیدواژه‌ها English

Hypertension
Regional blood flow
Aerobic Exercise
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مجله دانشکده پزشکی اصفهان
دوره 35، شماره 425 - شماره پیاپی 425
خرداد و تیر 1396
صفحه 368-375

  • تاریخ دریافت 29 آبان 1395
  • تاریخ پذیرش 17 فروردین 1401