نکروز جلدی پس از تزریق سدیم استیبوگلوکونات جهت درمان لیشمانیوز جلدی: گزارش یک مورد نادر

نوع مقاله : نامه به سردبیر

نویسندگان

1 استادیار، مرکز تحقیقات پوست و سالک و گروه‌ پوست، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

2 استادیار، گروه بیماری‌های عفونی و گرمسیری، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

3 استادیار، گروه داروسازی بالینی، دانشکده‌ی داروسازی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران

4 دانشجوی پزشکی، کمیته‌ی تحقیقات دانشجویی، دانشکده‌ی پزشکی، دانشگاه علوم پزشکی اصفهان، اصفهان، ایران

5 دستیار تخصصی داروسازی بالینی، کمیته‌ی تحقیقات دانشجویی و گروه داروسازی بالینی، دانشکده‌ی داروسازی، دانشگاه علوم پزشکی شهید بهشتی، تهران، ایران

چکیده

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کلیدواژه‌ها


عنوان مقاله [English]

Cutaneous Necrosis after the Injection of Sodium Stibogluconate for the Treatment of Cutaneous Leishmaniasis: A Rare Case Report

نویسندگان [English]

  • Bahareh Abtahi-naeini 1
  • Atousa Hakamifard 2
  • Zahra Sahraei 3
  • Mahdi Hadian 4
  • Ali Saffaei 5
1 Assistant Professor, Skin Diseases and Leishmaniasis Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
2 Assistant Professor, Department of Infectious Diseases, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
3 Assistant Professor, Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4 Student of Medicine, Student Research Committee, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
5 Resident of Clinical Pharmacy, Student Research Committee AND Department of Clinical Pharmacy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran
چکیده [English]

A 32-year-old man was diagnosed with cutaneous leishmaniasis, and intradermal Sodium Stibogluconate was injected for him. After two days, the injection site became erythematous, and a progressive necrotizing lesion appeared; hence, the patient diagnosed with soft tissue infection. Antibiotic therapy and debridement initiated for him. Cutaneous adverse effect of Sodium Stibogluconate is not common, and among them, coetaneous necrosis is rare. Sodium Stibogluconate is a mixture of complex compound, and it is not a simple medicine. A probable mechanism of necrosis formation in this case is hypersensitivity reactions. Hence, it is suggested to avoid intradermal injection of this medicine, especially those brands which do not claim intradermal injection allowance.

کلیدواژه‌ها [English]

  • Necrosis
  • Leishmaniasis
  • Sodium stibogluconate
  • Soft tissue infection
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