نوع مقاله : مقاله های پژوهشی
1 استادیار ،گروه بیهوشی، دانشکدهی پزشکی، دانشگاه علوم پزشکی کردستان، سنندج، ایران
2 دانشیار، گروه بیهوشی، دانشکدهی پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران
3 استاد، گروه بیهوشی، دانشکدهی پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران
4 پزشک عمومی، دانشکده پزشکی، دانشگاه علوم پزشکی ارومیه، ارومیه، ایران
عنوان مقاله [English]
Background: Postoperative nausea and vomiting (PONV) is the most common and unpleasant postoperative complication. It seems that fluid-therapy during the surgery is effective on the onset of this complication. The aim of this study was to compare the effect of 30 and 10 ml/kg crystalloid infusion on PONV after laparoscopic cholecystectomy under general anesthesia.Methods: In this study, 146 patients who were randomly divided into two equal groups were evaluated. One group received 30 ml/kg and the other 10 ml/kg Ringer solution as a preoperative intravenous bolus. The incidence and intensity of PONV, and the need for a rescue antiemetic were recorded by anesthesiologist in recovery, and 6, 12, and 24 hours after surgery.Findings: The incidence of PONV was not significantly difference between the two groups. The intensity of vomiting in group 30 ml/kg was significantly lower 12 hours after surgery (P < 0.01). The antiemetic drugs were used significantly less in group 30 ml/kg than other group.Conclusion: Preoperative intravenous administration of 30 ml/kg crystalloid compared with crystalloid 10 ml/kg in patients undergoing laparoscopic cholecystectomy did not reduce the incidence of nausea and vomiting, but reduced the intensity of vomiting 12 hours after surgery, and antiemetic use 24 hours after surgery.