کاربرد طب مکمل برروی عملکرد جنسی زنان یائسه: : مرور سیستماتیک

نوع مقاله : مقاله مروری

نویسندگان

1 کارشناسی ارشد، گروه مامایی، دانشکده‌ی پرستاری و مامایی، علوم پزشکی مشهد، دانشگاه آزاد اسلامی، مشهد، ایران

2 استادیار، مرکز تحقیقات مراقبت‌های مادر و کودک، دانشگاه علوم پزشکی هرمزگان، بندرعباس، ایران

چکیده

مقاله مروری




مقدمه: عملکرد جنسی، یکی از جنبه‌های مهم زندگی زنان یائسه می‌باشد. عوارض طولانی‌مدت درمان‌های جایگزین هورمونی در دوره‌ی یائسگی، زنان را به سوی استفاده از درمان‌های مکمل برای بهبود عملکرد جنسی سوق داده است. این مرور سیستماتیک با هدف بررسی اثربخشی استفاده از درمان‌های مکمل برای بهبود عملکرد جنسی زنان یائسه انجام شد.
روش‌ها: در این مطالعه‌ی مروری سیستماتیک، جستجوی مطالعات به زبان انگلیسی و فارسی در پایگاه داده‌های ملی همچون SID، Magiran،  IranMedexو پایگاه‌های بین‌المللی همچون PubMed، Science Direct، Embase، Cochrane Library و موتور جستجوگر Google Scholar تا سال 2023 انجام شد. کلیدواژه‌ها بر اساس MeSH انتخاب گردید و شامل "Sexual Dysfunctions"، "Menopause"، "Complementary medicine"، ""Alternative medicine بودند که با عملگرهای بولین OR و AND ترکیب شدند. در نهایت دو پژوهشگر به‌طور مستقل مقالات انتخاب شده را جهت ارزیابی کیفیت (با استفاده از ابزار استاندارد کوکران) و استخراج یافته‌ها مورد بررسی قرار دادند.
یافته‌ها: در نهایت 22 مقاله با حجم نمونه‌ی کلی 1617 نفر انتخاب شد. مطالعات نشان داد که رایحه درمانی، آروماتراپی استنشاقی ترکیبی و استفاده از ترکیبات گیاهی مانند مصرف کپسول‌های گیاهی ترکیبی از جمله عصاره‌ی جینسنگ قرمز، زعفران، شبدر قرمز و کوهوش سیاه، گرده خرما و گیاه ختمی، منجر به بهبود عملکرد جنسی زنان یائسه شده بود. همچنین انجام فعالیت‌هایی مانند یوگا، آرام‌سازی بنسون و مداخله‌ی شناختی- رفتاری بیشترین تأثیر را بر عملکرد جنسی داشته است.
نتیجه‌گیری: بر اساس نتایج پژوهش حاضر، اکثر درمان‌های طب مکمل بر بهبود عملکرد جنسی زنان یائسه تأثیر داشت.

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Usability of Complementary Medicine in Sexual Performance of Postmenopausal Women: A Systematic Review

نویسندگان [English]

  • Fahimeh Tahonian Golkhatmi 1
  • Dina Abadi Bavil 1
  • Mojdeh Banaei 2
1 MSc, Department of Midwifery, Mashhad Branch, Islamic Azad University, Mashhad, Iran
2 Assistant Professor, Mother and Child Welfare Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran
چکیده [English]

Background: Sexual performance is among the most important aspects of postmenopausal women's life. The long-term side effects of hormone replacement therapy during menopause have led women towards the use of complementary therapies to improve sexual performance. This systematic review was conducted to investigate the effectiveness of complementary therapies in improving the sexual performance of postmenopausal women.
Methods: In this systematic review, studies in English and Persian languages were searched in national (SID, Magiran, and IranMedex) and international databases (PubMed, Science Direct, Embase, Cochrane Library, and Google Scholar) until 2023. The search keywords were selected based on the Medical Subject Heading (MeSH) and included "Sexual Dysfunctions", "Menopause", "Complementary medicine", and "Alternative medicine" combined with Boolean operators (OR and AND). Finally, quality assessment and data extraction were performed independently by two researchers using Cochran's standard tool.
Findings: Finally, 22 articles with a total sample size of 1617 participants were selected. The types of the articles were randomized and non-randomized clinical trials. Studies showed that aroma therapy, combined inhalation aromatherapy, and herbal compounds, including combined herbal capsules containing red ginseng extract, saffron, red clover and black cohosh, date palm pollen, and Althaea officinalis improved sexual performance in menopausal women. Furthermore, performing activities, including yoga, Benson relaxation, and CBT had the greatest effect on sexual performance.
Conclusion: Based on the results of the present study, most complementary medicine treatments were effective in improving the sexual performance of postmenopausal women.

کلیدواژه‌ها [English]

  • Complementary therapies
  • Sexual dysfunction
  • Menopause
  • Herbal medicine

مراجع

  1. Arman S, Fahami F, Hasan Zahraee R. A comparative Study on women’s sexual functioning disorders before and after menopause [in Persian]. J Arak Uni Med Sci 2006; 8(3): 1-7.
  2. Bosak Z, Iravani M, Moghimipour E, Haghighizadeh MH, Jelodarian P, Khazdair MR. Evaluation of the influence of chamomile vaginal gel on dyspareunia and sexual satisfaction in postmenopausal women: A randomized, double-blind, controlled clinical trial. Avicenna J Phytomed 2020; 10(5): 481-91.
  3. Karimi F, Babazadeh R, Zojaji A, Jouya S. Squill oil for decreasing dyspareunia and increasing sexual satisfaction in menopausal women: A triple-blind randomized controlled trial. Avicenna J Phytomed 2021; 11(5): 464-72.
  4. Sadeghi S, Yosefzadeh S, Mahrozadeh S, Mazloum SR, Rakhshandeh H. The effect of date palm pollen capsule on female sexual interest/arousal disorder in menopausal woman [in Persian]. JIITM 2019; 9(4): 287-96.
  5. Mazalzadeh F, Hekmat K, Namjoyan F, SakiMalehi A. Effect of fenugreek vaginal cream on dyspareunia and sexual satisfaction in menopausal women: A randomized clinical trial [in Persian]. The Iran J Obstet Gynecol Infertil 2018; 21(3): 22-30.
  6. Abbaspoor Z, Sharifipour F, Siahposh A, Nazaralivand R, Mohaghegh Z, Siahkal SF. Effects of aromatherapy with citrus aurantium lavender on sexual function of postmenopausal women: A randomized controlled trial. J Family Reprod Health 2022; 16(2): 147-54.
  7. Malakouti J, Farshbaf Khalili A, Asghari Jafarabadi M, Jabbari F. Effect of combined inhaler aromatherapy on sexual function in postmenopausal women: a randomized controlled trial [in Persian]. The Iran J Obstet Gynecol Infertil 2016; 19(1.2): 9-15.
  8. Rashidi Ahmad Abadi M, Valiani M, Kabir K, Khalajinia Z, Yazdkhasti M. The effectiveness of auriculotherapy on women's sexual function: A randomized controlled trial. Iran J Psychiatry 2022; 17(3): 265-75.
  9. Tabatabaeichehr M, Nazari S, Bagheri M, Niazi I, Abassi Z, Soltani M, et al. Effect of oral saffron on sexual function of postmenopausal women: A clinical trial study [in Persian]. The Iran J Obstet Gynecol Infertil 2020; 22(12): 46-53.
  10. Amiri Pebdani M, Taavoni S, Haghani H. Effect of ginkgo biloba extract on sexual activity in 50-60 years menopausal women in Tehran [in Persian]. CMJA 2012; 2(2): 148-58.
  11. Khayatan J, Iravani M, Moghimipour E, Haghighizadeh MH, Jelodarian P. The effect of red clover vaginal cream on sexual function in postmenopausal women: A randomized, controlled clinical trial [in Persian]. The Iran J Obstet Gynecol Infertil 2019; 22(8): 26-34.
  12. Sarayloo K, Latifnejad Roudsari R. Critical evaluation of the published clinical trials regarding the effect of complementary medicine on menopausal symptoms [in Persian]. The Iran J Obstet Gynecol Infertil 2018; 21(4): 87-98.
  13. Salarfard M, Yazdimoghaddam H, Abdollahi M, Karimi FZ. The effect of herbal medicines on vaginal atrophy in postmenopausal women: A systematic review and meta-analysis [in Persian]. The Iran J Obstet Gynecol Infertil 2022; 24(13): 100-18.
  14. Koliji T, Keshavarz Z, Zare E, Mojab F, Nasiri M. A systematic review of herbal medicines to improve the sexual function of menopausal women. J Herbmed Pharmacol 2020; 10(1): 51-60.
  15. osefzadeh S, Sadeghi S, Rakhshandeh H, Dadghar S, Mazloum SR. The effect of date palm pollen capsule on orgasm and sexual satisfaction in menopausal women: a double-blind controlled clinical trial [in Persian]. The Iran J Obstet Gynecol Infertil 2017; 20(10): 43-51.
  16. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJM, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Control Clin Trials 1996; 17(1): 1-12.
  17. Rostamkhani F, Ghamari M, Babakhani V, Effat-al-Sadat Merghati Khoei E. The effectiveness of “cognitive-behavioral therapy” on the sexual function and schema of postmenopausal women [in Persian]. Journal of Health Promotion Management 2020; 9(6): 96-107.
  18. Nazarpour S, Simbar M, Majd HA, Tehrani FR. Beneficial effects of pelvic floor muscle exercises on sexual function among postmenopausal women: a randomised clinical trial. Sex Health 2018; 15(5): 396-402.
  19. Nazarpour S, Simbar M, Ramezani Tehrani F, Alavi Majd H. Effects of sex education and Kegel exercises on the sexual function of postmenopausal women: a randomized clinical trial. The journal of sexual medicine 2017; 14(7): 959-67.
  20. de Souza KZD, Vale FBC, Geber S. Efficacy de Souza of Tribulus terrestris for the treatment of hypoactive sexual desire disorder in postmenopausal women: a randomized, double-blinded, placebo-controlled trial. Menopause 2016; 23(11): 1252-6.
  21. Postigo S, Lima SMRR, Yamada SS, Reis BFd, Silva GMDd, Aoki T. Assessment of the effects of Tribulus terrestris on sexual function of menopausal women. Rev Bras Ginecol Obstet 2016; 38(3): 140-6.
  22. Oh KJ, Chae MJ, Lee HS, Hong HD, Park K. Effects of Korean red ginseng on sexual arousal in menopausal women: placebo-controlled, double-blind crossover clinical study. J Sex Med 2010; 7(4 Part 1): 1469-77.
  23. Johnson AK, Johnson AJ, Barton D, Elkins G. Hypnotic relaxation therapy and sexual function in postmenopausalwomen: Results of a randomized clinical trial. Int J Clin Exp Hypn 2016; 64(2): 213-24.
  24. Abedi P, Najafian M, Yaralizadeh M, Namjoyan F. Effect of fennel vaginal cream on sexual function in postmenopausal women: a double blind randomized controlled trial. J Med Life 2018; 11(1): 24-8.
  25. Eliasvandi P, Khodaie L, Mohammad Alizadeh Charandabi S, Mirghafourvand M. Efficacy of combined herbal capsule on sexual function in postmenopausal women: a triple-blind randomized controlled trial. International Journal of Women's Health and Reproduction Sciences. 2019; 7(3): 385-92.
  26. Ghorbani Z, Mirghafourvand M, Mohammad-Alizadeh Charandabi S, Javadzadeh Y. The effect of ginseng on sexual dysfunction in menopausal women: A double-blind, randomized, controlled trial. Complement Ther Med 2019; 45: 57-64.
  27. Kianitalaei A, Qaraaty M, Hamedi S, Akhlaghi F, Behnampour N, Feyzabadi Z. Effect of Alcea on sexual function in postmenopausal women: a randomized, controlled clinical trial [in Persian]. The Iran J Obstet Gynecol Infertil 2021; 23(11): 24-32.
  28. Tavoni S, Amiri Pebdani M, Haghghani H. Effect of ginkgo biloba extract on sexual activity in 50-60 years menopausal women in Tehran [in Persian]. J Sabzevar Univ Med Sci 2014; 20(2): 204-12.
  29. Bagetta G, Morrone LA, Rombolà L, Amantea D, Russo R, Berliocchi L, et al. Neuropharmacology of the essential oil of bergamot. Fitoterapia 2010; 81(6): 453-61.
  30. Hur MH, Yang YS, Lee MS. Aromatherapy massage affects menopausal symptoms in Korean climacteric women: a pilot-controlled clinical trial. Evid Based Complement Alternat Med 2008; 5(3): 325-8.
  31. Al-Qarawi AA, Mousa HM, Ali B, Abdel-Rahman H, El-Mougy SA. Protective effect of extracts from dates (Phoenix dactylifera L.) on carbon tetrachloride-induced hepatotoxicity in rats. Int J Appl Res Vet Med 2004; 2(3): 176-80.
  32. Amin ES, Awad O, Abd El Samad M, Iskander M. Isolation of estrone from Moghat roots and from pollen grains of Egyptian date palm. Phytochemistry. 1969; 8(1): 295-7.
  33. Hassan HM. Chemical composition and nutritional value of palm pollen grains. Global J Biotechnol Biochem 2011; 6(1): 1-7.
  34. Mahran GH, Abdel–Wahab SM, Attia AM. A phytochemical study of date palm pollen. Planta Med 1976; 29(2): 171-5.
  35. Ranjbar H, Ashrafizaveh A. Effects of saffron (Crocus sativus) on sexual dysfunction among men and women: A systematic review and meta-analysis. Avicenna J Phytomed 2019; 9(5): 419-27.
  36. Gaeini AA. Effect of complementary saffron and resistance training on serum levels of growth hormone, insulin-like growth factor-1 and testosterone in young men [in Persian]. Iranian J Endocrinol Metabol. 2018; 20(4): 177-84.
  37. Alaei M, Hosseini SA, Azarbayjani MA. The effect of a period resistance training with saffron extract supplementation on testosterone, FSH and LH of rats [in Persian]. JSB 2014; 3(12): 86-77.
  38. Tedeschi C, Benvenuti C, Research Group EG.
    Comparison of vaginal gel isoflavones versus no topical treatment in vaginal dystrophy: results of a preliminary prospective study. Gynecol Endocrinol 2012; 28(8): 652-4.
  39. Kim SY, Seo SK, Choi YM, Jeon YE, Lim KJ, Cho S, et al. Effects of red ginseng supplementation on menopausal symptoms and cardiovascular risk factors in postmenopausal women: a double-blind randomized controlled trial. Menopause 2012; 19(4): 461-6.
  40. Al-Snafi AE. The pharmaceutical importance of Althaea officinalis and Althaea rosea: A review. Int J Pharm Tech Res 2013; 5(3): 1387-5.
  41. Kianitalaei A, Feyzabadi Z, Hamedi S, Qaraaty M. Althaea officinalis in traditional medicine and modern phytotherapy. J Adv Pharm Educ Res 2019; 9(S2): 155-61.
  42. Golzareh P, Rahimi R, Rahimikian F, Bekhradi R, Mehran A. The effect of fennel oral capsules on physical symptoms caused by menopause in women [in Persian]. Iranian J Obstetr, Gynecol Infertil 2017; 20(9): 41-8.
  43. Badgujar SB, Patel VV, Bandivdekar AH. Foeniculum vulgare Mill: a review of its botany, phytochemistry, pharmacology, contemporary application, and toxicology. Biomed Res Int 2014; 2014: 842674.
  44. Najar S, Yaralizadeh M, Abedi P, Namjooyan F, Malehi O. Effect of fennel vaginal cream on dysparonia and sexual satisfaction among postmenopausal women: a double-blind randomized controlled trial [in Persian]. The Iran J Obstet Gynecol Infertil 2015; 18(171): 8-16.
  45. Abdali K, Dowran P, Kasraian M, Tabatabaei H. Comparison of the effect of foeniculum vulgare and effect of Foeniculum vulgare and St Johns wort (Hypericum perforatum) on the climacteric symptoms and sexual activity in menopausal women attending in selected gynecology. Int J Adv Biol Res 2013; 7(1): 148-54.
  46. Yoshikawa M, Murakami T, Komatsu H, Murakami N, Yamahara J, Matsuda H. Medicinal foodstuffs. IV. Fenugreek seed.(1): structures of trigoneosides Ia, Ib, IIa, IIb, IIIa, and IIIb, new furostanol saponins from the seeds of Indian Trigonella foenum-graecum L. Chem Pharm Bull (Tokyo) 1997; 45(1): 81-7.
  47. Krum H, Schlaich M, Whitbourn R, Sobotka PA, Sadowski J, Bartus K, et al. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet 2009; 373(9671): 1275-81.
  48. Akhtari E, Raisi F, Keshavarz M, Hosseini H, Sohrabvand F, Bioos S, et al. Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo-controlled study. DARU 2014; 22(1): 1-7.
  49. T Tadayon M, Shojaee M, Afshari P, Moghimipour E, Haghighizadeh MH. The effect of hydro-alcohol extract of Tribulus terrestris on sexual satisfaction in postmenopause women: A double-blind randomized placebo-controlled trial. J Family Med Prim Care 2018; 7(5): 888-92.
  50. Martino-Andrade AJ, Morais RN, Spercoski KM, Rossi SC, Vechi MF, Golin M, et al. Effects of Tribulus terrestris on endocrine sensitive organs in male and female Wistar rats. J Ethnopharmacol 2010; 127(1): 165-70.
  51. Gauthaman K, Ganesan AP. The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction-an evaluation using primates, rabbit and rat. Phytomedicine 2008; 15(1-2): 44-54.
  52. Gama CR, Lasmar R, Gama GF, Abreu CS, Nunes CP, Geller M, et al. Clinical assessment of Tribulus terrestris extract in the treatment of female sexual dysfunction. Clin Med Insights Womens Health 2014; 7: 45-50.
  53. Goudarzi F, Mohamadzadeh Vatanchi A, Mirzaei Najmabadi K. Impact of Tribulus Terrestris on male fertility: systematic review and meta-analysis [in Persian]. The Iran J Obstet Gynecol Infertil 2019; 22(3): 76-86.
  54. Abadibavil D, Shariat Moghani S, Rashidpour MH, Jamali J. The effectiveness of Benson relaxation methods on menopausal complications in postmenopausal women [in Persian]. The Iran J Obstet Gynecol Infertil 2021; 24(6): 58-68.
  55. Abedimanesh N, Ostadrahimi A, Bathaie SZ, Abedimanesh S, Motlagh B, Jafarabadi MA, et al. Effects of saffron aqueous extract and its main constituent, crocin, on health-related quality of life, depression, and sexual desire in coronary artery disease patients: a double-blind, placebo-controlled, randomized clinical trial. Iran Red Crescent Med J 2017; 19(9): e13676.
  56. Palacios S, Soler E, Ramírez M, Lilue M, Khorsandi D, Losa F. Effect of a multi-ingredient based food supplement on sexual function in women with low sexual desire. BMC Womens Health 2019; 19(1): 58.
  57. Gerber JR, Johnson JV, Bunn JY, O'Brien SL. A longitudinal study of the effects of free testosterone and other psychosocial variables on sexual function during the natural traverse of menopause. Fertil Steril 2005; 83(3): 643-8.
  58. Dąbrowska J, Drosdzol A, Skrzypulec V, Plinta R. Physical activity and sexuality in perimenopausal women. Eur J Contracept Reprod Health Care 2010; 15(6): 423-32.
  59. Haimov-Kochman R, Constantini N, Brzezinski A, Hochner-Celnikier D. Regular exercise is the most significant lifestyle parameter associated with the severity of climacteric symptoms: a cross sectional study. Eur J Obstet Gynecol Reprod Biol 2013; 170(1): 229-34.
  60. Ferreira CHJ, Dwyer PL, Davidson M, De Souza A, Ugarte JA, Frawley HC. Does pelvic floor muscle training improve female sexual function? A systematic review. Int Urogynecol J 2015; 26(12): 1735-50.
مجله دانشکده پزشکی اصفهان
دوره 41، شماره 724
هفته 4 مرداد
مرداد و شهریور 1402
صفحه 496-510

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  • تاریخ دریافت: 14 خرداد 1402
  • تاریخ پذیرش: 28 تیر 1402

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