اثر تمرین ورزشی و رژیم غذایی، به تنهایی، بر هموگلوبین گلیکوزیله (HbA1c) و گلوکز ناشتا در بیماران مبتلا به دیابت نوع یک: مطالعه‌ی مرور نظام‌مند فراتحلیل

نوع مقاله : مقاله مروری

نویسندگان

1 استادیار، گروه تربیت بدنی و علوم ورزشی، دانشکده علوم انسانی، دانشگاه کاشان، کاشان، ایران

2 دانشجوی کارشناسی ارشد، گروه تربیت بدنی و علوم ورزشی، دانشکده علوم انسانی، دانشگاه کاشان، کاشان، ایران

چکیده

مقاله مروری



مقدمه: بیماری دیابت نوع یک (Type 1 Diabetes) T1D، یک بیماری خودایمنی است. بهترین راه کنترل T1D، کنترل سطح قند خون، تغییر سبک زندگی از جمله رژیم غذایی مناسب و فعالیت بدنی است. هدف از مطالعه‌ی حاضر، بررسی اثر تمرین ورزشی و رژیم غذایی، به تنهایی، بر هموگلوبین گلیکوزیله
(glycated hemoglobin, HbA1c) و گلوکز ناشتا در بیماران T1D بود.
روش‌ها: جستجوی سیستماتیک در پایگاه‌های اطلاعاتی PubMed، Web of Science، Scopus و Google Scholar برای مقالات انگلیسی منتشر شده تا اکتبر 2022 انجام شد. فراتحلیل برای بررسی اثر تمرین ورزشی و رژیم غذایی، به تنهایی، بر HbA1c و گلوکز ناشتا در بیماران مبتلا به T1D انجام گردید. تفاوت میانگین استاندارد شده (Standardized mean difference) SMD، تفاوت میانگین وزنی (Weighted mean difference) WMD و فاصله‌ی اطمینان 95 درصد با استفاده از مدل اثر تصادفی محاسبه شد.
یافته‌ها: نتایج 14 مطالعه با 637 دختر و پسر مبتلا به T1D نشان داد که تمرین ورزشی، سبب کاهش معنی‌دار HbA1c (0/03 = P، 0/55- = SMD) در بیماران T1D نسبت به گروه شاهد شد. اما تمرین ورزشی، سبب کاهش معنی‌دار گلوکز ناشتا (0/07 = P، mg/dL14/28- = WMD) در بیماران T1D نسبت به گروه شاهد نشد. همچنین رژیم غذایی باعث کاهش معنی‌دار HbA1c (0/6 = P، 0/04- = SMD) و گلوکز ناشتا (0/1 = P ،mg/dL 18/52- = WMD) در بیماران T1D نسبت به گروه شاهد نشد.
نتیجه‌گیری: مطالعه‌ی حاضر نشان داد که تمرین ورزشی به عنوان یک راهکار غیردارویی برای کاهش HbA1c برای بیماران T1D پیشنهاد می‌شود. با توجه به نتایج فراتحلیل حاضر، مناسب‌ترین شیوه‌ی تمرین برای کاهش HbA1c، تمرین ترکیبی است. اما رژیم غذایی به تنهایی اثری بر HbA1c در بیماران T1D ندارد.

تازه های تحقیق

فاطمه کاظمی نسب: Google Scholar, PubMed

کلیدواژه‌ها

موضوعات

عنوان مقاله [English]

The Effect of Exercise Training and Diet, Alone, on Glycosylated Hemoglobin (HbA1c) and Fasting Glucose in Patients with Type 1 Diabetes: A Meta-Analysis Systematic Review

نویسندگان [English]

  • Fatemeh Kazeminasab 1
  • Saideh Ahmadinejad 2
1 Assistant Professor, Department of Physical Education and Sport Sciences, Faculty of Humanities, University of Kashan, Kashan, Iran
2 MSc Student, Department of Physical Education and Sport Sciences, Facultyof Humanities, University of Kashan, Kashan, Iran
چکیده [English]

Background: Type 1 diabetes (T1D) is an autoimmune disease. The best way to control T1D is to control blood sugar levels and change lifestyle, including proper diet and physical activity. This study aimed to investigate the effect of exercise and diet alone on glycated hemoglobin (HbA1c) and fasting glucose in patients with T1D.
Methods: A systematic search was conducted in PubMed, Web of Science, Scopus, and Google Scholar databases for English articles published until October 2022. A meta-analysis was performed to investigate the effect of exercise and diet, alone, on HbA1c and fasting glucose in patients with T1D. Standardized mean difference (SMD), weighted mean difference (WMD), and 95% confidence interval were calculated using a random effect model.
Findings: The results of 14 studies with 637 boys and girls with T1D showed that exercise caused a significant decrease in HbA1c (P = 0.03, SMD = -0.55) in T1D patients compared to the control group. However, exercise did not significantly reduce fasting glucose (P = 0.07, WMD = -28.14 mg/dL) in T1D patients compared to the control group. Also, the diet did not significantly reduce HbA1c (SMD-0.04, P = 0.6) and fasting glucose (WMD-18.52 mg/dL, P = 0.1) in patients with T1D compared to the control group.
Conclusion: The present study shows that exercise training is suggested as a non-pharmacological solution to reduce HbA1c for T1D patients. According to the results of the present meta-analysis, the most appropriate exercise method to reduce HbA1c is combined exercise. However, diet alone does not affect HbA1c in patients with T1D.

کلیدواژه‌ها [English]

  • Exercise
  • Diet
  • Glycosylated hemoglobin
  • Glucose
  • Type 1 diabetes

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مجله دانشکده پزشکی اصفهان
دوره 41، شماره 742
هفته 2، دی
آذر و دی 1402
صفحه 988-1003

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  • تاریخ دریافت: 29 مهر 1402
  • تاریخ پذیرش: 16 دی 1402

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