مجله دانشکده پزشکی اصفهان

مجله دانشکده پزشکی اصفهان

تأثیر 8 هفته تمرین مقاومتی به همراه مصرف مکمل ایزو وی ایزوله بر سطوح سرمی اکتیوین A، دکورین و و TGF-β در مردان میانسال

نوع مقاله : Original Article(s)

نویسندگان
1 گروه تربیت بدنی و علوم ورزشی، واحد شوشتر، دانشگاه آزاد اسلامی، شوشتر، ایران
2 گروه فیزیولوژی ورزشی، دانشکده‌ی تربیت بدنی و علوم ورزشی، دانشگاه خوارزمی، تهران، ایران
10.48305/jims.v44.i873.2024
چکیده
مقدمه: عضله‌ی اسکلتی به عنوان عضوی شناخته می‌شود که می‌تواند مولکول‌هایی با عملکردهای حیاتی تولید کند. هدف این پژوهش تعیین تأثیر ۸ هفته تمرین مقاومتی و مصرف مکمل ایزووی بر میزان اکتیوین A، دکورین و و TGF-β در مردان میانسال بود.
روش‌ها: مطالعه به صورت نیمه‌تجربی و کاربردی انجام شد. جامعه‌ی آماری شامل مردان کم‌تحرک ۴۰ تا ۴۵ سال بندر ماهشهر بود. ۴۰ نفر به صورت هدفمند انتخاب و به چهار گروه تمرین مقاومتی، مکمل، تمرین+مکمل و کنترل (هر گروه ۱۰ نفر) تقسیم شدند. تمرین مقاومتی به مدت ۸ هفته، سه جلسه در هفته، با شدت ۶۰ تا ۷۰ درصد یک تکرار بیشینه انجام شد. مکمل ۲۵ گرم پروتئین وی ایزوله دو بار در روز پس از صبحانه و ناهار مصرف شد. داده‌ها با آزمون آنالیز واریانس دوطرفه در سطح معنی‌داری 0/05 تجزیه و تحلیل شدند.
یافته‌ها: در گروه تمرین (0/001 = P)، مکمل (0/01 = P) و تمرین+مکمل (0/001 = P) مقدار اکتیوین A کاهش معناداری داشت. در گروه تمرین (0/001 = P)، مکمل (0/01 = P) و تمرین+مکمل (0/001 = P) مقدار دکورین کاهش معناداری داشت. در گروه تمرین (0/003 = P) و تمرین+مکمل (0/001 = P) مقدار TGF-β کاهش معناداری داشت.
نتیجه‌گیری: تمرین به تنهایی و در تعامل با پروتئین وی اثر بهتری در بهبود مایوکاین های موثر در هاپیرتروفی عضلانی دارد.

تازه های تحقیق

مطهره شکاریان: Google Scholar

کلیدواژه‌ها
موضوعات

عنوان مقاله English

The effect of 8 weeks of resistance training combined with the use of Iso Whey Isolate supplementation on serum levels of Activin A, Decorin, and TGF-β in middle-aged men

نویسندگان English

Motahereh Shekarian 1
Meysam Shabaninia 1
Hamid Rajabi 2
Mohammad Sajjadian 1
1 Department of Physical Education and Sport Science, Sho.C., Islamic Azad University, Shoushtar, Iran
2 Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, Kharazmi University, Tehran, Iran
چکیده English

Background: Skeletal muscle is recognized as an organ capable of producing molecules with vital biological functions. The aim of this study was to determine the effects of 8 weeks of resistance training and Iso-Whey supplementation on serum levels of Activin A, Decorin, and TGF-β in middle-aged men.
Methods: This study was conducted using a semi-experimental and applied design. The statistical population consisted of sedentary men aged 40–45 years in Bandar Mahshahr. Forty participants were purposively selected and randomly assigned to four groups: resistance training, supplementation, training+supplementation, and control (10 participants per group). Resistance training was performed for 8 weeks, three sessions per week, at an intensity of 60–70% of one-repetition maximum. The supplement consisted of 25 g of whey protein isolate consumed twice daily after breakfast and lunch. Data were analyzed using two-way analysis of variance (ANOVA) at a significance level of P ≤ 0.05.
Findings: Serum Activin A levels showed a significant decrease in the training (P = 0.001), supplementation (P = 0.01), and training+supplementation (P = 0.001) groups. Serum Decorin levels also decreased significantly in the training (P = 0.001), supplementation (P = 0.01), and training+supplementation (P = 0.001) groups. A significant reduction in TGF-β levels was observed in the training (P = 0.003) and training+supplementation (P = 0.001) groups.
Conclusion: Resistance training alone and in combination with whey protein supplementation appears to have a superior effect on improving myokines involved in muscular hypertrophy.

کلیدواژه‌ها English

Myokine
Resistance Training
Whey protein
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دوره 44، شماره 873
ویژه‌نامه پزشکی ورزشی
مرداد و شهریور 1405
صفحه 2024-2034

  • تاریخ دریافت 11 دی 1404
  • تاریخ بازنگری 14 بهمن 1404
  • تاریخ پذیرش 01 بهمن 1404