مجله دانشکده پزشکی اصفهان

مجله دانشکده پزشکی اصفهان

تأثیر ترتیب تمرینات ترکیبی شنا بر شاخص‌های التهابی و آنتی‌اکسیدانی عضله EDL در رت‌های مسن

نوع مقاله : Original Article(s)

نویسندگان
1 دانشجوی کارشناسی ارشد، گروه فیزیولوژی ورزشی، دانشکده‌ی علوم ورزشی، دانشگاه بوعلی سینا، همدان، ایران
2 استاد، گروه فیزیولوژی ورزشی، دانشکده‌ی علوم ورزشی، دانشگاه بوعلی، همدان، ایران
3 دانشجو دکتری، گروه فیزیولوژیورزشی، دانشکده‌ی علوم ورزشی، دانشگاه بوعلی سینا، همدان، ایران
10.48305/jims.v44.i851.0150
چکیده
مقدمه: با توجه به اهمیت تمرینات ورزشی در دوران سالمندی، این مطالعه به بررسی تأثیر ترتیب اجرای تمرینات ترکیبی (اینتروال-استقامتی) بر شاخص‌های التهابی و آنتی‌اکسیدانی در عضله EDL رت‌های مسن پرداخت.
روش‌ها: 15 رت نر ویستار مسن (1820 ماهه) به‌صورت تصادفی در سه گروه کنترل (Cont)، تمرین کانکارنت اینتروال- استقامتی (IE) و تمرین کانکارنت استقامتی- اینتروال (EI) تقسیم شدند. مداخله تمرینی طی 10 هفته (5 جلسه/هفته) انجام و شدت (4-12 درصد وزن بدن) و مدت (25-45 دقیقه) تمرین هفتگی افزایش یافت. 48 ساعت پس از آخرین جلسه، عضله EDL برداشته شد و سطوح پروتئینی شاخص‌ها با روش الایزا اندازه‌گیری شد (سطح معنی‌داری 0/05 > P).
یافته‌ها: گروه‌های  IEو EI در مقایسه با کنترل کاهش معنی‌داری در IL-1β نشان دادند. فعالیت (Superoxide dismutase) SOD در هر دو گروه تمرینی نسبت به کنترل افزایش معنی‌داری یافت. بالاترین سطح IL-10 در گروه‌های IE و EI مشاهده شد (0/05 > P)؛ اگرچه گروه EI افزایش 44 درصدی را نشان داد، دامنه تغییرات آن نسبت به گروهIE  81 درصد کمتر بود.
نتیجه‌گیری: نتایج نشان داد، پروتکل IE نسبت به EI اثربخشی معنی‌دارتری دارد، در حالی که تغییرات القا شده توسط EI محدودتر بود. این یافته‌ها بیانگر نقش کلیدی ترتیب اجرای تمرین کانکارنت در تعدیل پاسخ‌های التهابی و آنتی‌اکسیدانی عضله سالمندان است.
 

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کلیدواژه‌ها
موضوعات

عنوان مقاله English

The Effect of Swimming Concurrent Training Order on Inflammatory and Antioxidant Indices in the EDL Muscle of Aged Rats

نویسندگان English

Ali Moradi 1
Hesam Parsa 2
Narges Torkzaban 1
Hamidreza Choobdari 3
1 MSc Student, Department of Exercise Physiology, Faculty of Sport Sciences, Bu-Ali Sina University, Hamedan, Iran
2 Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Bu-Ali Sina University, Hamedan, Iran
3 PhD Student, Department of Exercise Physiology, Faculty of Sport Sciences, Bu-Ali Sina University, Hamedan, Iran
چکیده English

Introduction:Considering the importance of exercise in aging, this study examined the effect of concurrent training order (interval-endurance) on inflammatory and antioxidant indices in the EDL muscle of aged rats.
Methods: 15 aged male Wistar rats (18–20 months) were randomly divided into three groups: control (Cont), interval-endurance training (IE), and endurance-interval training (EI). The 10-week training intervention (5 sessions/week) was performed, with intensity (4-12% of body weight) and duration (25-45 minutes) progressively increasing weekly. 48 hours after the last session, the EDL muscle was removed, and protein levels of indices were measured by ELISA (significance level set at P < 0.05).
Results: Both IE and EI groups showed a significant decrease in IL-1β protein levels compared to the control group. SOD enzyme activity was also significantly increased in both IE and EI groups versus the control. For IL-10, both IE and EI groups exhibited the highest levels of this anti-inflammatory cytokine (P < 0.05); however, although the EI group showed a 44% increase, the magnitude of change was smaller compared to the IE group (81%).
Discussion: The results indicated that the IE protocol had significantly greater effectiveness than the EI protocol, while the changes induced by EI were more limited in scope. These findings suggest that the order of performing concurrent training components plays a key role in modulating inflammatory and antioxidant responses in the muscle of the elderly.

کلیدواژه‌ها English

EDL muscle
Concurrent training
Training sequence
Inflammatory cytokines
Antioxidant enzyme
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دوره 44، شماره 851
هفته 3، فروردین
فروردین و اردیبهشت 1405
صفحه 150-157

  • تاریخ دریافت 17 دی 1404
  • تاریخ پذیرش 17 خرداد 1405