Background
Today, diabetes is one of the most common comorbidities and risk factors in patients with tuberculosis (TB). The present study examines the trend of the disease burden of TB attributed to high fasting plasma glucose (HFPG) in Iran during the years 1990 to 2021.
Methods
The present study analyzes data on mortality and DALYs from tuberculosis associated with high fasting blood glucose in Iran from 1990 to 2021. These data were extracted from the Global Burden of Disease Database (2021). In addition, the relationship of these items with the Human Development Index was measured by calculating Pearson's correlation.
Findings
The burden of TB disease attributed to HFPG in Iran has been decreasing during 1990-2021. Sistan and Baluchestan, Golestan, and Khorasan Razavi provinces showed the highest burden of TB attributed to HFPG, and Tehran province showed the highest percentage decrease in the burden change. There is a negative and significant correlation between the HDI and the DALY of TB attributed to HFPG (r=-0.378, p-value=0.035) and the YLD (Years Lived with Disability) attributed to HFPG (r=-0.449, p-value=0.011).
Conclusion
Although Iran has been successful in reducing the burden of TB attributed to HFPG, there are significant regional inequalities. Improving human development indicators and implementing targeted interventions in deprived areas can help further reduce this burden.